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一名婴儿感染人疱疹病毒7型过程中的脑炎

Encephalitis in the Course of HHV-7 Infection in an Infant.

作者信息

Moppert Justyna, Łężyk-Ciemniak Eliza, Pawłowska Małgorzata

机构信息

Department of Infectious Diseases and Hepatology, Collegium Medicum, Bydgoszcz, Nicolaus Copernicus University, 87-100 Torun, Poland.

Department of Paediatrics, Infectious Diseases and Hepatology, Voivodeship Infectious Observation Hospital, 85-030 Bydgoszcz, Poland.

出版信息

J Clin Med. 2024 Jan 12;13(2):418. doi: 10.3390/jcm13020418.

DOI:10.3390/jcm13020418
PMID:38256552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10816044/
Abstract

Most cases of acute infections caused by human herpesvirus 7 (HHV-7) are asymptomatic or very mild. Clinical symptoms disappear spontaneously; however, the infection becomes latent and persists for life with periodic asymptomatic reactivation. Little is known about the virus's ability to cross the blood-brain barrier. Our case of an immunocompetent infant indicates that HHV-7 infection should be considered a cause of neuroinfection, not only in immunocompromised patients but also in the youngest immunocompetent patients.

摘要

大多数由人类疱疹病毒7型(HHV - 7)引起的急性感染病例是无症状的或非常轻微的。临床症状会自发消失;然而,感染会转为潜伏状态并终身持续,伴有周期性的无症状再激活。关于该病毒穿越血脑屏障的能力知之甚少。我们这位免疫功能正常的婴儿病例表明,HHV - 7感染不仅在免疫功能低下的患者中,而且在最年幼的免疫功能正常的患者中,都应被视为神经感染的一个病因。

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Reactivation of herpesviruses during COVID-19: A systematic review and meta-analysis.新冠疫情期间疱疹病毒再激活:系统评价和荟萃分析。
Rev Med Virol. 2023 May;33(3):e2437. doi: 10.1002/rmv.2437. Epub 2023 Mar 7.
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Human Herpes Virus 7-related encephalopathy in children.儿童人类疱疹病毒 7 型相关性脑炎。
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