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心率变异性自动识别考虑呼吸成分的高压状态。

Heart Rate Variability to Automatically Identify Hyperbaric States Considering Respiratory Component.

机构信息

Centro Universitario de la Defensa de Zaragoza, 50090 Zaragoza, Spain.

BSICoS Group, I3A Institute, University of Zaragoza, IIS Aragón, 50009 Zaragoza, Spain.

出版信息

Sensors (Basel). 2024 Jan 11;24(2):0. doi: 10.3390/s24020447.

DOI:10.3390/s24020447
PMID:38257541
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11154234/
Abstract

This study's primary objective was to identify individuals whose physiological responses deviated from the rest of the study population by automatically monitoring atmospheric pressure levels to which they are exposed and using parameters derived from their heart rate variability (HRV). To achieve this, 28 volunteers were placed in a dry hyperbaric chamber, where they experienced varying pressures from 1 to 5 atmospheres, with five sequential stops lasting five minutes each at different atmospheric pressures. The HRV was dissected into two components: the respiratory component, which is linked to respiration; and the residual component, which is influenced by factors beyond respiration. Nine parameters were assessed, including the respiratory rate, four classic HRV temporal parameters, and four frequency parameters. A k-nearest neighbors classifier based on cosine distance successfully identified the atmospheric pressures to which the subjects were exposed to. The classifier achieved an 88.5% accuracy rate in distinguishing between the 5 atm and 3 atm stages using only four features: respiratory rate, heart rate, and two frequency parameters associated with the subjects' sympathetic responses. Furthermore, the study identified 6 out of 28 subjects as having atypical responses across all pressure levels when compared to the majority. Interestingly, two of these subjects stood out in terms of gender and having less prior diving experience, but they still exhibited normal responses to immersion. This suggests the potential for establishing distinct safety protocols for divers based on their previous experience and gender.

摘要

本研究的主要目的是通过自动监测志愿者所暴露的大气压水平,并利用他们的心率变异性(HRV)参数,识别出那些生理反应与研究人群其他成员不同的个体。为了实现这一目标,我们让 28 名志愿者置身于干燥高压舱中,让他们经历从 1 到 5 个大气压的不同压力,每次在不同的大气压下持续 5 分钟,共进行 5 个阶段的逐步加压。我们将 HRV 分为两部分:与呼吸相关的呼吸分量,以及受呼吸以外因素影响的剩余分量。研究评估了 9 个参数,包括呼吸频率、4 个经典 HRV 时间参数和 4 个频率参数。基于余弦距离的 k-最近邻分类器成功识别了志愿者所暴露的大气压水平。该分类器仅使用 4 个特征(呼吸频率、心率和与志愿者交感反应相关的两个频率参数),就能以 88.5%的准确率区分 5 个大气压和 3 个大气压阶段。此外,与大多数志愿者相比,研究发现 28 名志愿者中有 6 名在所有压力水平下都存在非典型反应。有趣的是,其中两名非典型反应的志愿者在性别和潜水经验方面存在差异,但他们在浸没时仍表现出正常的反应。这表明有可能根据潜水员的既往经验和性别为他们制定不同的安全协议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb4a/11154234/96dd0fa28f6a/sensors-24-00447-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb4a/11154234/54c81bb579e3/sensors-24-00447-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb4a/11154234/0ebdad097dc9/sensors-24-00447-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb4a/11154234/1bf7e0f94d48/sensors-24-00447-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb4a/11154234/c8a5f845d61b/sensors-24-00447-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb4a/11154234/96dd0fa28f6a/sensors-24-00447-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb4a/11154234/54c81bb579e3/sensors-24-00447-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb4a/11154234/0ebdad097dc9/sensors-24-00447-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb4a/11154234/1bf7e0f94d48/sensors-24-00447-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb4a/11154234/c8a5f845d61b/sensors-24-00447-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb4a/11154234/96dd0fa28f6a/sensors-24-00447-g005.jpg

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本文引用的文献

1
Enhancing Safety in Hyperbaric Environments through Analysis of Autonomic Nervous System Responses: A Comparison of Dry and Humid Conditions.通过分析自主神经系统反应提高高压环境安全性:干燥和潮湿条件的比较。
Sensors (Basel). 2023 Jun 2;23(11):5289. doi: 10.3390/s23115289.
2
Autonomic Nervous System characterization in hyperbaric environments considering respiratory component and non-linear analysis of Heart Rate Variability.考虑呼吸成分和心率变异性的非线性分析的高压环境中的自主神经系统特征。
Comput Methods Programs Biomed. 2022 Feb;214:106527. doi: 10.1016/j.cmpb.2021.106527. Epub 2021 Nov 19.
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Photoplethysmographic Waveform and Pulse Rate Variability Analysis in Hyperbaric Environments.
高压环境下光体积脉搏波和脉搏率可变性分析。
IEEE J Biomed Health Inform. 2021 May;25(5):1550-1560. doi: 10.1109/JBHI.2020.3020743. Epub 2021 May 11.
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