Joye Raphael, Cousin Vladimir L, Malaspinas Iliona, Mwizerwa Leonce, Bouhabib Maya, Nalecz Tomasz, Sologashvili Tornike, Beghetti Maurice, L'Huillier Arnaud G, Wacker Julie
Pediatric Cardiology Unit, Department of Woman, Child, and Adolescent Medicine, Faculty of Medicine, Geneva University Hospitals, 1205 Geneva, Switzerland.
Pediatric Intensive Care Unit, Department of Woman, Child, and Adolescent Medicine, Faculty of Medicine, Geneva University Hospitals, 1205 Geneva, Switzerland.
Microorganisms. 2024 Jan 13;12(1):164. doi: 10.3390/microorganisms12010164.
Infective endocarditis due to is a rare but serious invasive infection that occurs mostly in children. Recent advances in nucleic acid amplification testing as well as in cardiac imaging have enabled more accurate diagnosis. A good understanding of the epidemiology and virulence factors remains crucial to guide the therapeutic approach. Here, we synthesize the current state of knowledge on epidemiological features, pathophysiological insights, complications, and therapy regarding endocarditis in children and adults. Finally, throughout this comprehensive review, knowledge gaps and areas for future research are also identified.
由……引起的感染性心内膜炎是一种罕见但严重的侵袭性感染,主要发生在儿童中。核酸扩增检测以及心脏成像方面的最新进展使得诊断更加准确。深入了解流行病学和毒力因子对于指导治疗方法仍然至关重要。在此,我们综合了关于儿童和成人……心内膜炎的流行病学特征、病理生理学见解、并发症及治疗的当前知识状况。最后,在这篇全面综述中,还确定了知识空白和未来研究领域。 (原文中“due to”后缺少具体病因,翻译时保留了该表述的不完整性)