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原发性去分化十二指肠脂肪肉瘤伴胃出口梗阻:一种罕见的小肠肿瘤。

Primary Dedifferentiated Duodenal Liposarcoma With Gastric Outlet Obstruction: A Rare Small Bowel Tumor.

作者信息

Alvi Ali Tariq, Shankar Murali

机构信息

Internal Medicine, HCA Florida Westside Hospital, Plantation, USA.

出版信息

Cureus. 2023 Dec 23;15(12):e50978. doi: 10.7759/cureus.50978. eCollection 2023 Dec.

DOI:10.7759/cureus.50978
PMID:38259374
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10801394/
Abstract

Liposarcoma is the most prevalent malignant soft tissue tumor and is primarily found in extremities and retroperitoneum, but its occurrence within abdominal viscera is rare. Most of these cases have been reported in the esophagus and stomach. Among liposarcomas of the gastrointestinal tract, primary duodenal liposarcomas are exceptionally rare, with only five documented cases in the literature. We describe a case of a 66-year-old female presenting with syncope, melena, and anemia. Computed tomography (CT) showed soft tissue mass involving the superior wall of the duodenum and hypo-enhancing hepatic mass. An endoscopy was performed, which revealed a duodenal mass causing gastric outlet obstruction and significant bleeding. Therefore, laparotomy was performed with extensive lysis of adhesions and gastrojejunostomy.

摘要

脂肪肉瘤是最常见的恶性软组织肿瘤,主要见于四肢和腹膜后,但发生于腹腔脏器者罕见。其中大多数病例报道于食管和胃。在胃肠道脂肪肉瘤中,原发性十二指肠脂肪肉瘤极为罕见,文献中仅有5例记录。我们描述了一例66岁女性,表现为晕厥、黑便和贫血。计算机断层扫描(CT)显示十二指肠上壁软组织肿块及肝脏低密度强化肿块。行内镜检查,发现十二指肠肿块导致胃出口梗阻并大量出血。因此,行剖腹手术,广泛松解粘连并行胃空肠吻合术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74b4/10801394/36e825588346/cureus-0015-00000050978-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74b4/10801394/a7145c6d49e7/cureus-0015-00000050978-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74b4/10801394/1c34fa77cebf/cureus-0015-00000050978-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74b4/10801394/36e825588346/cureus-0015-00000050978-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74b4/10801394/a7145c6d49e7/cureus-0015-00000050978-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74b4/10801394/1c34fa77cebf/cureus-0015-00000050978-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74b4/10801394/36e825588346/cureus-0015-00000050978-i03.jpg

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Primary Dedifferentiated Duodenal Liposarcoma With Gastric Outlet Obstruction: A Rare Small Bowel Tumor.原发性去分化十二指肠脂肪肉瘤伴胃出口梗阻:一种罕见的小肠肿瘤。
Cureus. 2023 Dec 23;15(12):e50978. doi: 10.7759/cureus.50978. eCollection 2023 Dec.
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本文引用的文献

1
Well Differentiated Liposarcoma Presenting as a Duodenal Polyp: A Case Report and Review of the Literature.高分化脂肪肉瘤表现为十二指肠息肉:病例报告及文献复习。
Int J Surg Pathol. 2023 May;31(3):307-311. doi: 10.1177/10668969221099628. Epub 2022 May 25.
2
Primary duodenal dedifferentiated liposarcoma: A case report and literature review.原发性十二指肠去分化脂肪肉瘤:一例报告及文献复习
World J Clin Cases. 2022 Feb 26;10(6):2007-2014. doi: 10.12998/wjcc.v10.i6.2007.
3
Primary duodenal liposarcoma, an exceedlingly rare small bowel tumour.
原发性十二指肠脂肪肉瘤,一种极其罕见的小肠肿瘤。
ANZ J Surg. 2022 Sep;92(9):2326-2327. doi: 10.1111/ans.17440. Epub 2021 Dec 29.
4
Retroperitoneal Liposarcoma Presenting With Malignant Gastric Outlet Obstruction and Acute Pancreatitis: A Case Report.以恶性胃出口梗阻和急性胰腺炎为表现的腹膜后脂肪肉瘤:一例报告
Cureus. 2021 Jan 18;13(1):e12775. doi: 10.7759/cureus.12775.
5
A Case of Primary Duodenal Liposarcoma.原发性十二指肠脂肪肉瘤1例。
Case Rep Oncol. 2020 Jun 11;13(2):649-654. doi: 10.1159/000507479. eCollection 2020 May-Aug.
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Well-differentiated liposarcoma and dedifferentiated liposarcoma: An updated review.高分化脂肪肉瘤和去分化脂肪肉瘤:最新综述。
Semin Diagn Pathol. 2019 Mar;36(2):112-121. doi: 10.1053/j.semdp.2019.02.006. Epub 2019 Feb 28.
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Soft Tissue Sarcoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.软组织肉瘤,2.2018 年版,NCCN 肿瘤学临床实践指南。
J Natl Compr Canc Netw. 2018 May;16(5):536-563. doi: 10.6004/jnccn.2018.0025.
8
Evolving Treatment of Soft Tissue Sarcoma.软组织肉瘤的治疗进展。
J Natl Compr Canc Netw. 2017 May;15(5S):733-736. doi: 10.6004/jnccn.2017.0087.
9
Primary liposarcoma of the duodenum: a first case presentation.十二指肠原发性脂肪肉瘤:首例病例报告
Intern Med. 2013;52(24):2753-7. doi: 10.2169/internalmedicine.52.1230.
10
Dedifferentiated liposarcoma: a clinicopathological analysis of 155 cases with a proposal for an expanded definition of dedifferentiation.去分化脂肪肉瘤:155例临床病理分析及去分化扩展定义的提议
Am J Surg Pathol. 1997 Mar;21(3):271-81. doi: 10.1097/00000478-199703000-00002.