Aoyama Jiro, Iha Hiroto, Ishikawa Mariko, Sagawa Hirotaka, Hirai Sakyo, Fujita Kyohei, Fujii Shoko, Sumita Kazutaka
Department of Endovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
J Neuroendovasc Ther. 2023;18(1):24-28. doi: 10.5797/jnet.cr.2023-0052. Epub 2023 Nov 18.
Cerebral venous sinus thrombosis (CVST) is one of the rare and severe complications of coronavirus disease 2019 (COVID-19) vaccines. CVST has also been reported to develop into dural arteriovenous fistula; however, there were no reports of dural arteriovenous fistula associated with COVID-19 vaccine-induced cerebral venous sinus thrombosis. Here, we describe a rare case of a transverse-sigmoid sinus dural arteriovenous fistula followed by CVST due to COVID-19 vaccination.
A 70-year-old patient presented with headache five days after receiving a second dose of COVID-19 vaccine. MRI showed a CVST in the superior sagittal sinus, left transverse sinus, and left sigmoid sinus. His headache improved after the administration of anticoagulant therapy. Six months later, a similar headache recurred, and cerebral angiography demonstrated a dural arteriovenous fistula in the left transverse sigmoid sinus and convexity dural arteriovenous fistulas in the left parietal cortex. The patient was treated twice with two sessions of transarterial embolization, and the shunts were completely occluded. His symptoms improved, and he was discharged with a modified Rankin Scale score of 0.
Dural arteriovenous fistula can develop after CVST in association with COVID-19 vaccination.
脑静脉窦血栓形成(CVST)是2019冠状病毒病(COVID-19)疫苗罕见且严重的并发症之一。据报道,CVST也可发展为硬脑膜动静脉瘘;然而,尚无与COVID-19疫苗诱导的脑静脉窦血栓形成相关的硬脑膜动静脉瘘的报道。在此,我们描述一例因接种COVID-19疫苗后发生横窦-乙状窦硬脑膜动静脉瘘并继发CVST的罕见病例。
一名70岁患者在接种第二剂COVID-19疫苗五天后出现头痛。MRI显示上矢状窦、左侧横窦和左侧乙状窦存在CVST。给予抗凝治疗后,他的头痛有所改善。六个月后,类似的头痛再次出现,脑血管造影显示左侧横窦乙状窦存在硬脑膜动静脉瘘,左侧顶叶皮质存在凸面硬脑膜动静脉瘘。该患者接受了两次经动脉栓塞治疗,分流完全闭塞。他的症状有所改善,出院时改良Rankin量表评分为0分。
与COVID-19疫苗接种相关的CVST后可发生硬脑膜动静脉瘘。