Eckert H, Engelmann C, Voigt H, Kaltwasser K, Danzmann E, Franz W D, Reutgen H, Grasshoff H J, Krüger A, Noack K
Z Exp Chir. 1979 Apr;12(2):74-83.
Morphologic Studies (light-microscopy, enzyme histochemistry, semi thin-layer preparation) on homografted canine lungs with and without immuno-suppressive therapy (Azathioprin, resp. anti-thymocyte serum) reveal different findings from untreated control animals and those after immuno-suppressive treatment. Under Azathioprin as well as anti-thymocyte serum the signs of rejection are attenuated, and regular pulmonary tissue is maintained in larger areas. Damages of certain cellular elements are better ascertained by means of determination of specific enzymes activities than by help of light-microscopic methods.
对接受和未接受免疫抑制治疗(分别使用硫唑嘌呤和抗胸腺细胞血清)的犬同种异体移植肺进行形态学研究(光学显微镜检查、酶组织化学、半薄切片制备),结果显示与未治疗的对照动物以及免疫抑制治疗后的动物存在不同的发现。在使用硫唑嘌呤和抗胸腺细胞血清的情况下,排斥反应的迹象减弱,更大面积的肺组织保持正常。通过测定特定酶活性比借助光学显微镜方法能更好地确定某些细胞成分的损伤情况。