过去 30 年世界卫生组织非洲区域控制、消除和消灭被忽视热带病的努力:范围综述。

Control, elimination, and eradication efforts for neglected tropical diseases in the World Health Organization African region over the last 30 years: A scoping review.

机构信息

World Health Organization Regional Office for Africa, B.P. 06 Cité de Djoué, Brazzaville, Congo; University of South Florida College of Public Health, 13201 Bruce B Downs Boulevard, Tampa, FL 33612, USA.

World Health Organization Regional Office for Africa, B.P. 06 Cité de Djoué, Brazzaville, Congo.

出版信息

Int J Infect Dis. 2024 Apr;141:106943. doi: 10.1016/j.ijid.2024.01.010. Epub 2024 Jan 22.

Abstract

OBJECTIVES

NTDs historically receive less attention than other diseases in the same regions. Recent gap analyses revealed notable shortcomings despite NTD elimination progress. This systematic scoping review was conducted to understand NTD control, elimination, and eradication efforts in the WHO African region over the last 30 years.

METHODS

Peer-reviewed publications from PubMed, Web of Science, and Cochrane databases related to NTD control, elimination, and eradication in the WHO African Region from 1990 to 2022 were reviewed. Included articles were categorized based on NTD; study location, type, and period; and topic areas. Technical and guidance documents from WHO, UN, partner, and academic/research institutions were reviewed. Country-specific multi-year NTD master plans were documented.

RESULTS

Four hundred eighty peer-reviewed articles, six Cochrane reviews, and 134 technical reports were included. MDA and non-interventional/survey-related studies were common topics. Lymphatic filariasis, trachoma, schistosomiasis, and onchocerciasis were the most frequently studied NTDs. Tanzania, Ethiopia, and Nigeria were the most represented countries; multi-country studies were limited.

CONCLUSION

The review highlights progress made in NTD control, elimination, and eradication efforts in the WHO African Region and can inform national/regional strategies. Disease and geographical disparities were evident, warranting focus and research in certain countries. A standardized approach to NTD control programs is needed for sustained progress.

FUNDING

There was no funding source for this study.

摘要

目的

与同一地区的其他疾病相比,历史上人们对热带病的关注较少。尽管在消除热带病方面取得了进展,但最近的差距分析显示仍存在明显的不足。本系统范围综述旨在了解过去 30 年来世卫组织非洲区域在控制、消除和消灭热带病方面所做的努力。

方法

检索 1990 年至 2022 年间在 PubMed、Web of Science 和 Cochrane 数据库发表的与世卫组织非洲区域热带病控制、消除和消灭相关的同行评审文献。根据热带病、研究地点、类型和时期以及主题领域对纳入的文章进行分类。还对来自世卫组织、联合国、合作伙伴以及学术/研究机构的技术和指导文件进行了审查。记录了各国具体的多年期热带病总体计划。

结果

共纳入 480 篇同行评审文章、6 篇 Cochrane 综述和 134 份技术报告。大规模驱虫和非干预性/调查相关研究是常见的主题。淋巴丝虫病、沙眼、血吸虫病和盘尾丝虫病是研究最多的热带病。坦桑尼亚、埃塞俄比亚和尼日利亚是出现频次最高的国家;多国家研究有限。

结论

本综述强调了世卫组织非洲区域在控制、消除和消灭热带病方面所取得的进展,并为国家/区域战略提供了信息。疾病和地理差异明显,需要在某些国家重点关注和开展研究。需要采用标准化方法来控制热带病,以实现持续进展。

资金

本研究无资金来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed2d/10927616/50e49a4f1315/gr1.jpg

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