Cloney Michael Brendan, Texakalidis Pavlos, Roumeliotis Anastasios G, Tecle Najib El, Dahdaleh Nader S
Department of Neurological Surgery, Feinberg School of Medicine of Northwestern University, Chicago, IL, USA.
J Craniovertebr Junction Spine. 2023 Oct-Dec;14(4):418-425. doi: 10.4103/jcvjs.jcvjs_126_23. Epub 2023 Nov 29.
Patients with simultaneous fractures of the atlas and dens have traditionally been managed according to the dens fracture's morphology, but data supporting this practice are limited.
We retrospectively examined all patients with traumatic atlas fractures at our institution between 2008 and 2016. We used multivariable regression and propensity score matching to compare the presentation, management, and outcomes of patients with isolated atlas fractures to patients with simultaneous atlas-dens fractures.
Ninety-nine patients were identified. Patients with isolated atlas fractures were younger (61 ± 22 vs. 77 ± 14, = 0.0003), had lower median Charlson Comorbidity Index (3 vs. 5, = 0.0005), had better presenting Nurick myelopathy scores (0 vs. 3, < 0.0001), and had different mechanisms of injury ( = 0.0011). Multivariable regression showed that having a simultaneous atlas-dens fracture was independently associated with older age (odds ratio [OR] =1.59 [1.22, 2.07], = 0.001), worse presenting myelopathy (OR = 3.10 [2.04, 4.16], < 0.001), and selection for surgery (OR = 4.91 [1.10, 21.97], = 0.037). Propensity score matching yielded balanced populations (Rubin's B = 23.3, Rubin's R = 1.96) and showed that the risk of atlas fracture nonunion was no different among isolated atlas fractures compared to simultaneous atlas-dens fractures ( = 0.304). Age was the only variable independently associated with atlas fracture nonunion (OR = 2.39 [1.15, 5.00], = 0.020), having a simultaneous atlas-dens fracture was not significant ( = 0.2829).
Among patients with atlas fractures, simultaneous fractures of the dens occur in older patients and confer an increased risk of myelopathy and requiring surgical stabilization. Controlling for confounders, the risk of atlas fracture nonunion is equivalent for isolated atlas fractures versus simultaneous atlas-dens fractures.
传统上,寰椎和齿突同时骨折的患者是根据齿突骨折的形态进行治疗的,但支持这种做法的数据有限。
我们回顾性研究了2008年至2016年间在我院接受治疗的所有创伤性寰椎骨折患者。我们使用多变量回归和倾向评分匹配方法,比较孤立性寰椎骨折患者与寰椎-齿突同时骨折患者的临床表现、治疗方式和治疗结果。
共纳入99例患者。孤立性寰椎骨折患者更年轻(61±22岁 vs. 77±14岁,P = 0.0003),Charlson合并症指数中位数更低(3 vs. 5,P = 0.0005),Nurick脊髓病评分更好(0 vs. 3,P < 0.0001),损伤机制也不同(P = 0.0011)。多变量回归显示,寰椎-齿突同时骨折与年龄较大独立相关(比值比[OR]=1.59[1.22, 2.07],P = 0.