Genomic and RNA Profiling Core Baylor College of Medicine HoustonTexas77030 USA.
Department of Education Innovation and Technology Baylor College of Medicine HoustonTexas77030 USA.
J Biomol Tech. 2023 Dec 4;34(4). doi: 10.7171/3fc1f5fe.30644720. eCollection 2023 Dec.
Core facility laboratories are an essential part of the successful research enterprise of many universities around the world. Core facilities provide state-of-the-art instrumentation and technologies to support research of all faculty, postdocs, and students on a fee-for-service basis. Academic next-generation sequencing cores are typically "full service" facilities, and access to and training on their instrumentation is limited to core staff. To address these limitations, we provided graduate students with technical training at our core facility. We developed a 1-week noncredit-bearing workshop and recruited 6 graduate students (N = 6) as part of a pilot program. The program involved online teaching, classroom-based teaching, and hands-on training in next-generation sequencing library preparation and sequencer operation. A post-participation survey revealed highly positive outcomes in terms of skill development and increased awareness of technologies offered by the core facility. A workshop of this scale could be incorporated into the graduate curriculum and extended to core facilities that focus on other technologies. We believe that introducing formal standardized teaching spearheaded by core facilities would improve the graduate student curriculum and hope that this study can provide guidance on curriculum design for similar workshops.
核心设施实验室是世界上许多大学成功开展研究工作的重要组成部分。核心设施提供最先进的仪器和技术,以按服务收费的方式为所有教师、博士后和学生的研究提供支持。学术下一代测序核心通常是“全方位服务”的设施,其仪器的使用和培训仅限于核心工作人员。为了解决这些限制,我们在我们的核心设施为研究生提供技术培训。我们开发了一个为期一周的无学分工作坊,并招募了 6 名研究生(N=6)作为试点计划的一部分。该计划包括在线教学、课堂教学以及下一代测序文库制备和测序仪操作方面的实践培训。参与后的调查显示,在技能发展和提高对核心设施提供的技术的认识方面取得了非常积极的成果。这种规模的研讨会可以纳入研究生课程,并扩展到专注于其他技术的核心设施。我们相信,引入由核心设施牵头的正式标准化教学将改进研究生课程,希望本研究能够为类似研讨会的课程设计提供指导。