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SARS-CoV-2 大流行期间在医院急诊死亡的患者特征:西班牙一家三级医院的回顾性队列研究。

Characteristics of patients who died in the hospital emergency service during the SARS-CoV-2 pandemic: a retrospective cohort study in a tertiary hospital in Spain.

机构信息

Hospital Universitario Germans Trias I Pujol, 08916, Badalona, Spain.

Hospital Universitario Marqués de Valdecilla, 39008, Santander, Cantabria, Spain.

出版信息

Intern Emerg Med. 2024 Jun;19(4):1109-1119. doi: 10.1007/s11739-023-03519-x. Epub 2024 Jan 25.

DOI:10.1007/s11739-023-03519-x
PMID:38270773
Abstract

The objective of this study is to analyze the characteristics of patients who died in the Hospital Emergency Department (HED) of a Spanish third-level hospital, with a special focus on those who died due to SARS-CoV-2. A retrospective cohort study was conducted, including all patients over 18 years old who died in the Hospital Emergency Department (HED) of a Spanish third-level hospital located in Badalona, Spain, from Jun 2019 to Dec 2020. Various sociodemographic, clinical, and diagnostic variables of the patients were analyzed to identify potential risk factors associated with mortality. During the first wave of the COVID-19 pandemic, a total of 72 patients died in the HED, representing a 42% increase compared to the pre-pandemic period. Of the deceased patients, 11% were attributed to SARS-CoV-2. Furthermore, it was found that patients who died from SARS-CoV-2 during the first wave were significantly younger than those in the second wave, with an average age of 78.6 ± 3.1 years in the first wave and 91.8 ± 4.8 years in the second wave. No significant differences were found regarding gender or associated comorbidities. Overall, the mortality rate at the HED in relation to COVID-19 was low, and infected patients died at younger ages during the first wave compared to the second wave.

摘要

本研究旨在分析在西班牙三级医院急诊部(HED)死亡的患者的特征,特别关注因 SARS-CoV-2 而死亡的患者。本研究采用回顾性队列研究方法,纳入了 2019 年 6 月至 2020 年 12 月期间在西班牙巴达洛纳一家西班牙三级医院 HED 死亡的所有年龄超过 18 岁的患者。分析了患者的各种社会人口学、临床和诊断变量,以确定与死亡率相关的潜在危险因素。在 COVID-19 大流行的第一波期间,HED 共有 72 名患者死亡,与大流行前相比增加了 42%。在死亡患者中,有 11%归因于 SARS-CoV-2。此外,研究还发现,第一波期间死于 SARS-CoV-2 的患者明显比第二波期间的患者年轻,第一波期间的平均年龄为 78.6±3.1 岁,第二波期间为 91.8±4.8 岁。性别或相关合并症方面没有显著差异。总体而言,HED 与 COVID-19 相关的死亡率较低,且感染患者在第一波期间的死亡年龄较第二波期间更年轻。

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