Shi Yong-Hong, Wang Qing-Ju, Huang Li-Zhen, Li Na, Ren Xin-Ting, Bi Shu-Min
Department of Infectious Disease, People's Hospital Affiliated to Shandong First Medical University, Jinan, China.
Department of General Medicine, People's Hospital Affiliated to Shandong First Medical University, Jinan, China.
Int Wound J. 2024 Jan;21(1):e14545. doi: 10.1111/iwj.14545.
This study aimed to systematically evaluate the impact of evidence-based nursing (EBN) on perioperative wound infections and postoperative complications in patients undergoing surgery for liver hepatocellular carcinoma (LIHC). Randomised controlled trials (RCTs) on the application of EBN on patients receiving LIHC surgery were searched in PubMed, Web of Science, Cochrane Library, Embase, Wanfang, China Biomedical Literature Database and China National Knowledge Infrastructure from the inception of each database to September 2023. Studies were screened and evaluated by two investigators based on inclusion and exclusion criteria, and data were extracted from the final included literature. RevMan 4.0 was used for data analysis. Overall, 15 RCTs involving 1374 patients with LIHC were included, with 687 in the EBN group and 687 in the conventional care group. The analysis revealed that the incidence of wound infections (odds ratio [OR] = 0.32, 95% confidence interval [CI]: 0.18-0.56, p < 0.001) and postoperative complications (OR = 0.22, 95% CI: 0.15-0.31, p < 0.001) was significantly lower in the EBN group than in the conventional care group. The available evidence suggests that nursing strategies for EBN applied in the perioperative period in patients with LIHC receiving surgery can effectively reduce the incidence of wound infections and postoperative complications and promote postoperative recovery.
本研究旨在系统评价循证护理(EBN)对肝细胞肝癌(LIHC)手术患者围手术期伤口感染及术后并发症的影响。从各数据库建库至2023年9月,在PubMed、Web of Science、Cochrane图书馆、Embase、万方、中国生物医学文献数据库和中国知网中检索关于EBN应用于接受LIHC手术患者的随机对照试验(RCT)。由两名研究者根据纳入和排除标准对研究进行筛选和评估,并从最终纳入的文献中提取数据。采用RevMan 4.0进行数据分析。共纳入15项RCT,涉及1374例LIHC患者,其中循证护理组687例,传统护理组687例。分析显示,循证护理组的伤口感染发生率(比值比[OR]=0.32,95%置信区间[CI]:0.18 - 0.56,p<0.001)和术后并发症发生率(OR=0.22,95%CI:0.15 - 0.31,p<0.001)显著低于传统护理组。现有证据表明,LIHC手术患者围手术期应用循证护理策略可有效降低伤口感染和术后并发症的发生率,促进术后恢复。