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袖状胃切除术后是否需要常规术后生物实验室评估?

Is Routine Post-operative Biological Laboratory Assessment Necessary After Sleeve Gastrectomy?

机构信息

Service de Chirurgie Digestive, Oesogastrique Et Bariatrique, Hôpital Bichat Claude Bernard, APHP, 75018, Paris, France.

Service de Chirurgie, GHI Le Raincy-Montfermeil, 93370, Montfermeil, France.

出版信息

Obes Surg. 2024 Mar;34(3):707-715. doi: 10.1007/s11695-024-07065-z. Epub 2024 Jan 26.

DOI:10.1007/s11695-024-07065-z
PMID:38273145
Abstract

BACKGROUND

Incidence of post-operative complications after sleeve gastrectomy (SG) is low. However, the early identification of these complications remains crucial. Here, we report the impact of routine laboratory monitoring for the early diagnosis of complications after SG.

MATERIAL AND METHODS

From January 2018 to December 2019, all consecutive patients who underwent primary SG (n = 457) were included. This was a comparative study of patients undergoing primary SG. Patients were divided into two groups: one group with routine laboratory monitoring performed at postoperative day (POD) 1 and 3 (LAB group) and another group without routine laboratory monitoring (control group). The study's primary endpoint was the overall impact of routine laboratory monitoring. The secondary endpoints were evaluation of patients with complications.

RESULTS

The population in the two groups were similar in term of demographic and intra-operative data. There was a statistical difference between the two groups in term of length of stay (5.7 days in the LAB group and 3.5 days in the control group (p < 0.001)). There were 19 complications (6.0%) in the LAB group and 5 complications in the control group (3.5%) (p = 0.25). A cut-off C-reactive protein level of 46.3 mg/l was found to be significant (p = 0.006). In the LAB group, 9 patients (2.9%) required readmission vs. three patients (2.0%) in the control group (p = 0.62).

CONCLUSION

The interest of routine laboratory monitoring after SG seems limited. Routine laboratory monitoring alone is not associated with earlier diagnosis of complications. This routine monitoring is associated with an increase of stay in hospital.

摘要

背景

袖状胃切除术(SG)后的术后并发症发生率较低。然而,早期识别这些并发症仍然至关重要。在这里,我们报告了常规实验室监测对 SG 后并发症早期诊断的影响。

材料和方法

从 2018 年 1 月至 2019 年 12 月,所有接受初次 SG 的连续患者(n=457)均被纳入研究。这是一项对接受初次 SG 的患者进行的对比研究。患者被分为两组:一组在术后第 1 天和第 3 天进行常规实验室监测(LAB 组),另一组不进行常规实验室监测(对照组)。该研究的主要终点是常规实验室监测的总体影响。次要终点是评估有并发症的患者。

结果

两组患者的人口统计学和术中数据相似。LAB 组的住院时间为 5.7 天,对照组为 3.5 天,两组之间存在统计学差异(p<0.001)。LAB 组有 19 例并发症(6.0%),对照组有 5 例并发症(3.5%)(p=0.25)。发现 C 反应蛋白水平为 46.3mg/L 时具有显著意义(p=0.006)。在 LAB 组,9 例患者(2.9%)需要再次入院,而对照组有 3 例患者(2.0%)(p=0.62)。

结论

SG 后常规实验室监测的意义似乎有限。单独进行常规实验室监测并不能更早地诊断并发症。这种常规监测与住院时间的延长有关。

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Challenges in the Diagnosis of Leak After Sleeve Gastrectomy: Clinical Presentation, Laboratory, and Radiological Findings.袖状胃切除术后漏的诊断挑战:临床表现、实验室和影像学表现。
Obes Surg. 2021 Feb;31(2):612-616. doi: 10.1007/s11695-020-05008-y. Epub 2020 Oct 6.
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J Visc Surg. 2020 Aug;157(4):317-327. doi: 10.1016/j.jviscsurg.2020.06.005. Epub 2020 Jun 5.
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