Heszler E, Szabó E
Acta Microbiol Acad Sci Hung. 1978;25(4):265-8.
The indirect immunofluorescent titres of Candida albicans 0656 CBS hyperimmune rabbit serum were investigated against C. albicans antigens prepared from strains originating from mucous membranes of healthy persons and patients with thrush. Using pathogenic strains as antigens, a definitely strong fluorescent reaction was obtained with hyperimmune rabbit serum in a dilution of 1 : 2500. In the case of apathogenic strains the fluorescent reaction was either very weak or negative in a dilution of 1 : 2000. Absorption studies also seemed to reveal a difference in reactivity between pathogenic and apathogenic strains. Hyperimmune rabbit serum absorbed with apathogenic C. albicans strains showed a positive fluorescent reaction only with pathogenic ones as antigens. In the opposite case a negative reaction was obtained.
研究了白色念珠菌0656 CBS超免疫兔血清针对从健康人和鹅口疮患者黏膜分离出的菌株制备的白色念珠菌抗原的间接免疫荧光滴度。以致病菌株作为抗原，超免疫兔血清在1:2500稀释度下可产生明确的强荧光反应。对于非致病菌株，在1:2000稀释度下荧光反应非常弱或呈阴性。吸收研究似乎也揭示了致病菌株和非致病菌株之间反应性的差异。用非致病性白色念珠菌菌株吸收的超免疫兔血清仅以致病菌株作为抗原时显示出阳性荧光反应。反之则得到阴性反应。
