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犬颈动脉体对冠状动脉血流、心肌氧化代谢及心脏儿茶酚胺的调控

Carotid body control of coronary flow, myocardial oxidative metabolism, and cardiac catecholamines in the dog.

作者信息

Limet R, Chabi E, Welch K M, Kennedy J H

出版信息

Recent Adv Stud Cardiac Struct Metab. 1976;9:269-78.

PMID:3828
Abstract

In a series of 11 dogs, selective stimulation of the carotid body receptors by hypoxic, hypercapnic, acidotic blood produces bradycardia, an increase of coronary flow, and greater release of norepinephrine from the heart; the coronary resistances are decreased. The same stimulation after vagotomy is no longer accompanied by bradycardia; the decrease of coronary resistance is less marked and the release of norephinephrine is increased.

摘要

在一组11只狗中,通过缺氧、高碳酸血症、酸中毒血液选择性刺激颈动脉体感受器会产生心动过缓、冠状动脉血流量增加以及心脏去甲肾上腺素释放增多;冠状动脉阻力降低。迷走神经切断术后进行同样的刺激不再伴有心动过缓;冠状动脉阻力降低不太明显,而去甲肾上腺素释放增加。

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