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一例左旋支支架感染及霉菌性动脉瘤的病例报告:经皮冠状动脉介入治疗罕见但危及生命的并发症

A case report of left circumflex stent infection and mycotic aneurysm: a rare but life-threatening complication of percutaneous coronary intervention.

作者信息

Kumar Swasthi S, Suresh Sumanyu, Iliyas Mohamed, Vijay Jyothi, Pillai Vivek

机构信息

Department of Cardiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, 695011, India.

Department of Cardiothoracic Surgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, 695011, India.

出版信息

Egypt Heart J. 2024 Jan 27;76(1):8. doi: 10.1186/s43044-024-00442-0.

Abstract

BACKGROUND

Coronary stent infections are an uncommon but deadly complication of percutaneous coronary intervention. Mortality remains as high as 40-60% even with adequate treatment. We report such an interesting case of left circumflex stent (LCX) infection and mycotic aneurysm that was successfully managed with antibiotics and surgery.

CASE PRESENTATION

A middle-aged man who underwent percutaneous coronary intervention (PCI) to the left circumflex artery four weeks prior was referred as a case of pyrexia of unknown origin, not responding to antibiotics, and colchicine started for suspected Dressler syndrome. Although the inflammatory markers were elevated, the results of the blood culture did not show any growth. Echocardiography showed a doubtful echogenic structure in the left atrioventricular groove and mild pericardial effusion, and a stent infection was suspected. PET scan showed focal metabolic activity in the region of the LCX stent, with metabolically active supraclavicular and paratracheal lymph nodes, and a coronary angiogram revealed an aneurysm arising distal to the stented LCX. A diagnosis of stent infection and associated mycotic aneurysm was made, and the patient underwent surgery which included aneurysm repair, stent retrieval, and coronary artery bypass graft (CABG) to the major and terminal OM. The postoperative course was uneventful, and the patient was discharged without complications.

CONCLUSIONS

It is important to investigate the possibility of coronary stent infection in individuals experiencing prolonged fever following PCI. PET scans and coronary angiograms can aid in diagnosis when echocardiograms are inconclusive. Adequate antibiotic therapy and timely surgery are crucial for successfully managing coronary stent infections.

摘要

背景

冠状动脉支架感染是经皮冠状动脉介入治疗中一种罕见但致命的并发症。即使经过充分治疗,死亡率仍高达40%-60%。我们报告了这样一例有趣的左旋支支架(LCX)感染合并霉菌性动脉瘤的病例,该病例通过抗生素和手术成功治愈。

病例介绍

一名中年男性,四周前接受了左旋支动脉的经皮冠状动脉介入治疗(PCI),因不明原因发热被转诊,对抗生素治疗无反应,因怀疑为德雷斯勒综合征开始使用秋水仙碱治疗。尽管炎症标志物升高,但血培养结果未显示任何细菌生长。超声心动图显示左房室沟有一个可疑的回声结构和轻度心包积液,怀疑有支架感染。PET扫描显示LCX支架区域有局灶性代谢活性,锁骨上和气管旁淋巴结有代谢活性,冠状动脉造影显示在植入支架的LCX远端出现一个动脉瘤。诊断为支架感染并伴有霉菌性动脉瘤,患者接受了手术,包括动脉瘤修复、支架取出以及对主要和终末钝缘支进行冠状动脉搭桥术(CABG)。术后过程顺利,患者无并发症出院。

结论

对于PCI后长期发热的患者,调查冠状动脉支架感染的可能性很重要。当超声心动图结果不明确时,PET扫描和冠状动脉造影有助于诊断。充分的抗生素治疗和及时的手术对于成功治疗冠状动脉支架感染至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c1/10821850/2e5ebcd6ff71/43044_2024_442_Fig1_HTML.jpg

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