Sangolkar Ravindra, Ketana Venkata Rajasekhara Rao, Sastry Bhagavatula Kutumba Srinivasa
Department of Cardiology, Care Hospitals, 5-4-199, Jawaharlal Nehru Road, Hyderabad, Telangana, India.
Eur Heart J Case Rep. 2018 Jun 4;2(2):yty067. doi: 10.1093/ehjcr/yty067. eCollection 2018 Jun.
Coronary artery stent infection is a rare event. We report a case of delayed coronary artery stent infection with coronary cameral fistula presented as pyrexia of unknown origin, 1 year after coronary intervention.
A 66-year-old man presented with paroxysmal low-grade fever of 2 years duration. He underwent percutaneous coronary intervention (PCI) with stent to right coronary artery (RCA) for inferior wall myocardial infarction in July 2014. He had non-ST-elevation myocardial infarction in December 2014. Repeat PCI with two stents to same vessel was done for total occlusion of stent. Repeated evaluations by family physician for fever did not yield any discrete diagnosis, and he was treated with empirical antibiotics. He had worsening of fever since last 2 months. Whole body positron emission tomography scan showed increased tracer uptake in RCA with perivascular abscess involving lateral wall of right ventricle. Coronary angiogram showed presence of small coronary cameral fistula from RCA draining into right atrium. Blood cultures grew . He was taken for surgery and the infected portion of the RCA including the stents was removed.
This case reports delayed coronary stent infection. Patient presented 1 year after procedure. Presence of bare metal stent increases risk of infection in presence of bacteraemia. Antiproliferative effects of drug eluting stents may predispose more to infection. This case was unique in its late presentation, presence of coronary cameral fistula and was successfully treated with surgery.
冠状动脉支架感染是一种罕见事件。我们报告一例冠状动脉介入治疗1年后出现的以不明原因发热为表现的迟发性冠状动脉支架感染合并冠状窦瘘病例。
一名66岁男性,有持续2年的阵发性低热。2014年7月,他因下壁心肌梗死接受了经皮冠状动脉介入治疗(PCI),在右冠状动脉(RCA)植入支架。2014年12月,他发生非ST段抬高型心肌梗死。因支架完全闭塞,对同一血管再次进行PCI并植入两枚支架。家庭医生对其发热进行了多次评估,但未得出明确诊断,遂给予经验性抗生素治疗。近2个月来,他的发热症状加重。全身正电子发射断层扫描显示RCA区域示踪剂摄取增加,伴有累及右心室侧壁的血管周围脓肿。冠状动脉造影显示存在一个从RCA引流至右心房的小冠状窦瘘。血培养有细菌生长。他接受了手术,切除了包括支架在内的RCA感染部分。
本病例报告了迟发性冠状动脉支架感染。患者在手术后1年出现症状。在存在菌血症的情况下,裸金属支架会增加感染风险。药物洗脱支架的抗增殖作用可能使感染倾向增加。本病例的独特之处在于其发病较晚、存在冠状窦瘘,且通过手术成功治愈。