单次口服去氧肾上腺素致脑梗死

Cerebral infarction with a single oral dose of phenylpropanolamine.

作者信息

Edwards M, Russo L, Harwood-Nuss A

出版信息

Am J Emerg Med. 1987 Mar;5(2):163-4. doi: 10.1016/0735-6757(87)90097-0.

Abstract

Phenylpropanolamine (PPA), a synthetic sympathomimetic that is structurally similar to amphetamine, is available over the counter in anorectics, nasal congestants, and cold preparations. Its prolonged use or overuse has been associated with seizures, intracerebral hemorrhage, neuropsychiatric symptoms, and nonhemorrhagic cerebral infarction. We report the case of a young woman who suffered a cerebral infarction after taking a single oral dose of PPA.

摘要

苯丙醇胺（PPA）是一种结构与苯丙胺相似的合成拟交感神经药，在用于治疗厌食症、缓解鼻充血和感冒的非处方药中可以买到。长期使用或过量使用PPA与癫痫发作、脑出血、神经精神症状以及非出血性脑梗死有关。我们报告了一名年轻女性在单次口服PPA后发生脑梗死的病例。