Coupe M O, Whittaker S J, Thatcher N
Br J Dermatol. 1987 Feb;116(2):245-7. doi: 10.1111/j.1365-2133.1987.tb05821.x.
A case of multicentric reticulohistiocytosis associated with a pleural mesothelioma is reported. The cutaneous and joint manifestations resolved after treatment with cyclophosphamide, and the remission persisted until the patient's death 3 years later. As corticosteroids have such an unpredictable effect on this condition, cyclophosphamide may be regarded as the treatment of choice until more cases can be assessed.
报告了一例与胸膜间皮瘤相关的多中心性网状组织细胞增生症。经环磷酰胺治疗后,皮肤和关节表现得到缓解,缓解状态一直持续到患者3年后死亡。由于皮质类固醇对这种疾病的疗效难以预测,在评估更多病例之前,环磷酰胺可被视为首选治疗药物。