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2型糖尿病患者起始胰岛素治疗的障碍:上海市南部惠南社区全科医生认知的研究

The Barriers to Insulin Therapy Initiation in Type 2 Diabetes Patients: A Study of General Practitioner Perceptions in Huinan Community in South Shanghai.

作者信息

Wen Song, Ruan Yufeng, Shi Zhongyu, Dan Shujie, Zhou Ligang

机构信息

Department of Endocrinology, Shanghai Pudong Hospital, Fudan University, Shanghai, People's Republic of China.

Department of General Practice, Huinan Health Service Center, Shanghai, People's Republic of China.

出版信息

Diabetes Metab Syndr Obes. 2024 Jan 24;17:393-405. doi: 10.2147/DMSO.S446349. eCollection 2024.

Abstract

BACKGROUND

Despite the demonstrated benefits of insulin therapy, many general practitioners (GPs) are hesitant to administer it due to challenges such as a lack of knowledge, time constraints, and patient reluctance. The barriers that prevent a GP from initiating insulin therapy may vary in comparison to those encountered by a diabetic patient; this aspect of clinical research in the South Shanghai metropolitan area has received limited attention so far.

OBJECTIVE

This is a 6-months of interventional analytic cohort study. The prime aim is to investigate the barriers general practitioners (GPs) face when initiating insulin therapy for patients with type 2 diabetes (T2D).

MATERIALS AND METHODS

As part of a training program, all 189 registered GPs in Nanhui Health Service Center in Shanghai were given a structured online-multi-choice questionnaire before and after a six-month interval, during which the GPs received sessions of training on insulin therapy either on theoretic classes or clinical practices.

RESULTS

Before and after training, via the methods of multiple-response analyses, the results showed that social, GP's, and patient barriers to initiating insulin therapy were comparable. However, through the crosstabs chi-square test, we found significant changes in the basal insulin initiation following the prescription of the senior endocrinologists, the titration of insulin, and the need for training (p<0.05). The Spearman analyses discovered significant changes associated with the cause of initial insulin refusal and the factors influencing insulin administration. Finally, the binary logistic regression analysis revealed that distinct causes such as social factors, insurance, GP experience, insulin dosage calculation, follow-up, and patients' feelings are related to insulin treatment application before and after training.

CONCLUSION

According to this study, training increased general practitioners' confidence in initiating insulin administration, especially basal insulin. General practitioners require additional education on insulin therapy, with a potential need for increased face-to-face training for insulin initiation.

摘要

背景

尽管胰岛素治疗已被证明具有诸多益处,但许多全科医生(GP)由于缺乏知识、时间限制和患者抵触等挑战,对使用胰岛素治疗仍犹豫不决。与糖尿病患者所面临的障碍相比,阻碍全科医生开始胰岛素治疗的障碍可能有所不同;到目前为止,上海南部大都市地区的这一临床研究方面受到的关注有限。

目的

这是一项为期6个月的干预性分析队列研究。主要目的是调查全科医生在为2型糖尿病(T2D)患者启动胰岛素治疗时所面临的障碍。

材料与方法

作为一项培训计划的一部分,上海南汇卫生服务中心的189名注册全科医生在间隔6个月前后分别接受了一份结构化的在线多项选择题问卷调查,在此期间,全科医生接受了胰岛素治疗的理论课程或临床实践培训。

结果

通过多反应分析方法,培训前后的结果显示,启动胰岛素治疗的社会、全科医生和患者障碍相当。然而,通过交叉表卡方检验,我们发现在内分泌科资深医生开出处方、胰岛素滴定以及培训需求后,基础胰岛素启动有显著变化(p<0.05)。Spearman分析发现与初始胰岛素拒绝原因和影响胰岛素给药的因素有显著变化。最后,二元逻辑回归分析显示,社会因素、保险、全科医生经验、胰岛素剂量计算、随访和患者感受等不同原因与培训前后的胰岛素治疗应用有关。

结论

根据这项研究,培训提高了全科医生启动胰岛素给药的信心,尤其是基础胰岛素。全科医生需要接受更多关于胰岛素治疗的教育,可能需要增加胰岛素启动的面对面培训。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/477d/10822111/934b77da70e3/DMSO-17-393-g0001.jpg

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