Cheon Soyeon, Li Chung-Yi, Jeng Jiann-Shing, Wang Jung-Der, Ku Li-Jung Elizabeth
Department of Public Health, College of Medicine, National Cheng Kung University, No.1, University Road, Tainan, 70101, Taiwan.
Department of Public Health, College of Public Health, China Medical University, Taichung, Taiwan.
Qual Life Res. 2024 Apr;33(4):991-1001. doi: 10.1007/s11136-023-03579-8. Epub 2024 Jan 29.
This work aimed to investigate the long-term dynamic changes of functional disabilities and estimate lifetime outcomes of different functional disabilities after a stroke, using real-world data from a nationally representative South Korean cohort.
Patients aged 18 and above with ischemic and hemorrhagic strokes were identified from the Korea Health Panel (KHP) data (2008-2018). Functional disabilities were repeatedly measured for patients aged 55 and over for the prevalence of disabilities associated with activities of daily living (ADL), and kernel smoothing means were estimated for each item. The lifetime survival function of stroke patients in Korea was adopted from another study utilizing the National Health Insurance Service of Korea's national sample cohort. By multiplying the disability-free proportion with the survival function throughout life, disability-free life expectancy (DFLE) for each ADL item was estimated. The loss-of-DFLE was calculated by subtracting the DFLE from age-, sex-, and calendar year-matched referents simulated from Korean life tables.
The KHP dataset included 466 stroke patients. The overall functional disability needs increased over time after stroke diagnosis. DFLE was lowest for bathing (10.1 years for ischemic stroke and 12.8 years for hemorrhagic stroke), followed by those for dressing and washing. Loss-of-DFLE was highest for bathing for ischemic and hemorrhagic strokes (7.2 and 10.7 years, respectively), indicating that this task required the most assistance for stroke patients compared with the other tasks. DFLEs were slightly lower than the quality-adjusted life expectancy of stroke patients.
Our findings provide valuable insights for resource allocation and policy decisions in long-term stroke care, potentially enhancing the quality of life for stroke survivors and caregivers.
本研究旨在利用韩国全国代表性队列的真实世界数据,调查功能残疾的长期动态变化,并估计中风后不同功能残疾的终生结局。
从韩国健康面板(KHP)数据(2008 - 2018年)中识别出年龄在18岁及以上的缺血性和出血性中风患者。对55岁及以上患者的功能残疾进行反复测量,以了解与日常生活活动(ADL)相关的残疾患病率,并对每个项目估计核平滑均值。韩国中风患者的终生生存函数取自另一项利用韩国国民健康保险服务全国样本队列的研究。通过将无残疾比例与终生生存函数相乘,估计每个ADL项目的无残疾预期寿命(DFLE)。DFLE损失通过从根据韩国生命表模拟的年龄、性别和日历年匹配的对照中减去DFLE来计算。
KHP数据集包括466名中风患者。中风诊断后,总体功能残疾需求随时间增加。洗澡的DFLE最低(缺血性中风为10.1年,出血性中风为12.8年),其次是穿衣和洗漱。缺血性和出血性中风洗澡的DFLE损失最高(分别为7.2年和10.7年),这表明与其他任务相比,中风患者在这项任务上需要的帮助最多。DFLE略低于中风患者的质量调整预期寿命。
我们的研究结果为长期中风护理中的资源分配和政策决策提供了有价值的见解,可能提高中风幸存者和护理人员的生活质量。