神经肌肉阻滞改善急性呼吸窘迫综合征的治疗效果：一种机制可能是预防呼气肌活动，从而使肺有更多扩张。 - Suppr

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Neuromuscular Blockade Improves Results in Acute Respiratory Distress Syndrome: A Mechanism May Be Prevention of Expiratory Muscle Activity, Which Allows More Lung Expansion.

作者信息

de Vries Heder Jonathan, Drummond Gordon

机构信息

Department of Critical Care Medicine Amsterdam University Medical Center Amsterdam, the Netherlands.

Amsterdam Cardiovascular Science Research Institute Amsterdam, the Netherlands.

出版信息

Am J Respir Crit Care Med. 2024 Mar 1;209(5):478-481. doi: 10.1164/rccm.202401-0012ED.

DOI:10.1164/rccm.202401-0012ED

PMID:38285592

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10919110/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad31/10919110/542f8c135c1a/rccm.202401-0012EDf1.jpg

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Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome.

N Engl J Med. 2019 May 23;380(21):1997-2008. doi: 10.1056/NEJMoa1901686. Epub 2019 May 19.

Acetylcholine receptor antagonists in acute respiratory distress syndrome: much more than muscle relaxants.

Crit Care. 2018 May 22;22(1):132. doi: 10.1186/s13054-018-1979-z.

Mechanical Ventilation-induced Diaphragm Atrophy Strongly Impacts Clinical Outcomes.

Am J Respir Crit Care Med. 2018 Jan 15;197(2):204-213. doi: 10.1164/rccm.201703-0536OC.

Effects of neuromuscular blockers on transpulmonary pressures in moderate to severe acute respiratory distress syndrome.

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Neuromuscular Blockade Improves Results in Acute Respiratory Distress Syndrome: A Mechanism May Be Prevention of Expiratory Muscle Activity, Which Allows More Lung Expansion.

作者信息

de Vries Heder Jonathan, Drummond Gordon

机构信息

Department of Critical Care Medicine Amsterdam University Medical Center Amsterdam, the Netherlands.

Amsterdam Cardiovascular Science Research Institute Amsterdam, the Netherlands.

出版信息

Am J Respir Crit Care Med. 2024 Mar 1;209(5):478-481. doi: 10.1164/rccm.202401-0012ED.

DOI:10.1164/rccm.202401-0012ED

PMID:38285592

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10919110/

Abstract

摘要

相似文献

Neuromuscular Blockade Improves Results in Acute Respiratory Distress Syndrome: A Mechanism May Be Prevention of Expiratory Muscle Activity, Which Allows More Lung Expansion.

Am J Respir Crit Care Med. 2024 Mar 1;209(5):478-481. doi: 10.1164/rccm.202401-0012ED.

Expiratory Muscle Activity Counteracts Positive End-Expiratory Pressure and Is Associated with Fentanyl Dose in Patients with Acute Respiratory Distress Syndrome.

Am J Respir Crit Care Med. 2024 Mar 1;209(5):563-572. doi: 10.1164/rccm.202308-1376OC.

Neuromuscular Blockers in Acute Respiratory Distress Syndrome: Flat Dose or Not. Are We Missing the Point?

Crit Care Med. 2020 May;48(5):e438. doi: 10.1097/CCM.0000000000004280.

Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome.

N Engl J Med. 2019 May 23;380(21):1997-2008. doi: 10.1056/NEJMoa1901686. Epub 2019 May 19.

Design and Rationale of the Reevaluation of Systemic Early Neuromuscular Blockade Trial for Acute Respiratory Distress Syndrome.

Ann Am Thorac Soc. 2017 Jan;14(1):124-133. doi: 10.1513/AnnalsATS.201608-629OT.

Personalized Positive End-Expiratory Pressure in Acute Respiratory Distress Syndrome: Comparison Between Optimal Distribution of Regional Ventilation and Positive Transpulmonary Pressure.

Crit Care Med. 2020 Aug;48(8):1148-1156. doi: 10.1097/CCM.0000000000004439.

Trials. 2022 Jan 31;23(1):96. doi: 10.1186/s13063-021-05927-w.

Pressure-volume curves with and without muscle paralysis in acute respiratory distress syndrome.

Intensive Care Med. 2006 Sep;32(9):1322-8. doi: 10.1007/s00134-006-0265-8. Epub 2006 Jul 7.

Positive end-expiratory pressure-induced functional recruitment in patients with acute respiratory distress syndrome.

Crit Care Med. 2010 Jan;38(1):127-32. doi: 10.1097/CCM.0b013e3181b4a7e7.

Effects of Positive End-Expiratory Pressure in "High Compliance" Severe Acute Respiratory Syndrome Coronavirus 2 Acute Respiratory Distress Syndrome.

Crit Care Med. 2020 Dec;48(12):e1332-e1336. doi: 10.1097/CCM.0000000000004640.

引用本文的文献

J Intensive Care. 2025 Feb 6;13(1):7. doi: 10.1186/s40560-025-00777-z.

Reply to Chi : Ventilator Waveforms May Give Clues to Expiratory Muscle Activity.

Am J Respir Crit Care Med. 2024 Jun 1;209(11):1408-1410. doi: 10.1164/rccm.202402-0360LE.

本文引用的文献

Expiratory Muscle Activity Counteracts Positive End-Expiratory Pressure and Is Associated with Fentanyl Dose in Patients with Acute Respiratory Distress Syndrome.

Am J Respir Crit Care Med. 2024 Mar 1;209(5):563-572. doi: 10.1164/rccm.202308-1376OC.

Expiratory muscle dysfunction in critically ill patients: towards improved understanding.

Intensive Care Med. 2019 Aug;45(8):1061-1071. doi: 10.1007/s00134-019-05664-4. Epub 2019 Jun 24.

Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome.

N Engl J Med. 2019 May 23;380(21):1997-2008. doi: 10.1056/NEJMoa1901686. Epub 2019 May 19.

Acetylcholine receptor antagonists in acute respiratory distress syndrome: much more than muscle relaxants.

Crit Care. 2018 May 22;22(1):132. doi: 10.1186/s13054-018-1979-z.

Mechanical Ventilation-induced Diaphragm Atrophy Strongly Impacts Clinical Outcomes.

Am J Respir Crit Care Med. 2018 Jan 15;197(2):204-213. doi: 10.1164/rccm.201703-0536OC.

Effects of neuromuscular blockers on transpulmonary pressures in moderate to severe acute respiratory distress syndrome.

Intensive Care Med. 2017 Mar;43(3):408-418. doi: 10.1007/s00134-016-4653-4. Epub 2016 Dec 24.

Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries.

JAMA. 2016 Feb 23;315(8):788-800. doi: 10.1001/jama.2016.0291.

Effects of an opioid on respiratory movements and expiratory activity in humans during isoflurane anaesthesia.

Respir Physiol Neurobiol. 2013 Jan 15;185(2):425-34. doi: 10.1016/j.resp.2012.08.016. Epub 2012 Aug 25.

Effects of airway occlusion on breathing muscle electromyogram signals, during isoflurane anaesthesia, with and without the effects of fentanyl and hypercapnia.

Br J Anaesth. 2011 Dec;107(6):989-97. doi: 10.1093/bja/aer301. Epub 2011 Sep 30.

Neuromuscular blockers in early acute respiratory distress syndrome.

N Engl J Med. 2010 Sep 16;363(12):1107-16. doi: 10.1056/NEJMoa1005372.