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院前过敏反应治疗期间静脉注射肾上腺素不当导致心房颤动:一例病例报告。

Inappropriate use of intravenous epinephrine leading to atrial fibrillation during prehospital anaphylaxis treatment: a case report.

作者信息

Jung Haewon, Ryoo Hyun Wook, Park Jungbae, Choi Seung Hyuk, Lee Jae Hyuk, Kim Sujeong

机构信息

Department of Emergency Medicine, Kyungpook National University School of Medicine, Daegu, Korea.

Armed Forces Medical Readiness and Training School, Daejeon, Korea.

出版信息

Clin Exp Emerg Med. 2024 Sep;11(3):304-308. doi: 10.15441/ceem.23.129. Epub 2024 Jan 29.

Abstract

In a prehospital setting, the narrow therapeutic window of epinephrine necessitates its cautious administration to avoid anaphylaxis. In this case, a 46-year-old man presented severe anaphylactic symptoms. Following the standard protocol, the emergency medical technician (EMT) administered intramuscular epinephrine; however, symptoms persisted. Under the oversight of the emergency medical services (EMS) medical director, an additional intravenous bolus of epinephrine was administered, unfortunately leading to atrial fibrillation. This case underscores the potential risks of intravenous epinephrine, which is not typically recommended for anaphylaxis without continuous monitoring. Since 2019, Korea has initiated a pilot program to expand the EMT scope of practice, which gives them the authority to administer epinephrine for anaphylaxis. The ultimate decision regarding epinephrine use for anaphylaxis, emphasizing patient safety, rests with the EMS medical director. Proper training for EMTs, coupled with the EMS medical director's comprehensive knowledge and meticulous protocol adherence, can ensure patient safety and optimal outcomes.

摘要

在院前环境中,肾上腺素狭窄的治疗窗使其在使用时需谨慎给药以避免过敏反应。在本病例中,一名46岁男性出现了严重的过敏症状。按照标准流程,急救医疗技术员(EMT)给予了肌内注射肾上腺素;然而,症状持续存在。在紧急医疗服务(EMS)医疗主任的监督下,又给予了一剂静脉推注肾上腺素,不幸的是导致了心房颤动。该病例突显了静脉注射肾上腺素的潜在风险,在没有持续监测的情况下,通常不建议将其用于过敏反应。自2019年以来,韩国启动了一项扩大急救医疗技术员执业范围的试点项目,赋予他们使用肾上腺素治疗过敏反应的权力。关于使用肾上腺素治疗过敏反应的最终决策,强调患者安全,由EMS医疗主任做出。对急救医疗技术员进行适当培训,再加上EMS医疗主任的全面知识和严格遵守规程,可确保患者安全并实现最佳治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb52/11467453/4dbc669759f9/ceem-23-129f1.jpg

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