Browning G G, Varma J S, Smith A N, Small W P, Duncan W
Br J Surg. 1987 Jan;74(1):31-4. doi: 10.1002/bjs.1800740111.
Ten patients with severe chronic irradiation injury to the rectum were treated by mucosal proctectomy and colo-anal sleeve anastomosis. The indications were: recurrent rectal bleeding (five), stricture (three), fistula (one) and intractable pain (one). Overall follow-up has ranged from 8 to 77 months (mean 40 months). In the present survivors (n = 7) the follow-up ranges from 18 to 77 months (mean 52 months). Six patients have been followed up for more than 3 years and four for more than 5 years. There was no operative mortality. Three anastomotic strictures occurred but the protecting stoma could be closed in all but one patient. Continence was acceptable although urgency and frequency of defaecation were troublesome symptoms. The operation is recommended for life-threatening, haemorrhagic chronic irradiation injury to the rectum.
对10例重度慢性直肠放射性损伤患者行直肠黏膜切除术及结肠肛管套入式吻合术。手术指征为:反复直肠出血(5例)、狭窄(3例)、瘘管形成(1例)及顽固性疼痛(1例)。总随访时间为8至77个月(平均40个月)。目前存活的患者(n = 7)随访时间为18至77个月(平均52个月)。6例患者随访超过3年,4例超过5年。无手术死亡病例。发生3例吻合口狭窄,但除1例外,其余患者的保护性造口均能关闭。尽管排便急迫感和排便次数增多是令人困扰的症状,但控便情况尚可接受。对于危及生命的直肠出血性慢性放射性损伤,推荐行此手术。