Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden.
Centre for Psychiatry Research, Stockholm County Health Care Provision, Stockholm, Sweden.
Neurogastroenterol Motil. 2024 Mar;36(3):e14744. doi: 10.1111/nmo.14744. Epub 2024 Jan 29.
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterized by diarrhea or constipation and other symptoms such as pain, bloating, and flatulence. The disease often has a negative effect on quality of life and is also associated with symptoms of anxiety and depression. Pharmacological treatments are not always effective, and complementary and alternative treatments are common.
We conducted a study on a group intervention based on the Ashtanga school of yoga. Fourteen participants (three men, 11 women; average age 51.4, SD = 16) were recruited from primary care, and 10 completed treatment. At pre-measurement, 4 participants had severe, 9 moderate, and 1 mild IBS, according to the IBS-SSS scale.
The intervention was regarded as credible (CEQ M = 39.2 SD = 8.8), and no serious adverse events were reported. The intervention showed significant effects on all measurements at post, as follows: IBS-SSS PRE (M = 272.0 SD = 75.5); IBS-SSS POST (M = 177.0 SD = 103.5); GSRS-IBS PRE (M = 48.4 SD = 15.9); GSRS-IBS POST (M = 37.4 SD = 12.4); VSI PRE (M = 38.8 SD = 10.0) VSI POST (M = 25.9 SD = 10.1); PHQ12 PRE (M = 10.0 SD = 4.3); PHQ12 POST (M = 6.9 SD = 4.3); HADS anxiety PRE (M = 8.9 SD = 5.0) HADS anxiety POST (M = 5.7 SD = 3.3) HADS depression PRE (M = 5.6 SD = 3.2) HADS depression POST (M = 3.8 SD = 2.9) IBS-QOL PRE (M = 64.5 SD = 12.5) IBS-QOL POST (M = 72.3 SD = 10.0). The effects were maintained at follow-up, except for general anxiety and depression. Preliminary effects at 3-month follow-up were in the moderate to large range for main outcomes.
CONCLUSION & INFERENCES: A 10-week group Ashtanga intervention was a feasible intervention for participants with IBS. Preliminary effects were promising and should be explored further in a randomized trial.
肠易激综合征（IBS）是一种常见的胃肠道疾病，其特征为腹泻或便秘以及疼痛、腹胀和呃逆等其他症状。该疾病常对生活质量产生负面影响，且与焦虑和抑郁症状相关。药物治疗并非总是有效，补充和替代疗法较为常见。
我们开展了一项基于阿斯汤加瑜伽流派的团体干预研究。从初级保健机构招募了 14 名参与者（3 名男性，11 名女性；平均年龄 51.4，SD=16），其中 10 名完成了治疗。根据 IBS-SSS 量表，治疗前，4 名参与者为严重 IBS，9 名为中度 IBS，1 名为轻度 IBS。
干预措施被认为是可信的（CEQ M=39.2，SD=8.8），且未报告严重不良事件。干预措施在治疗后所有测量指标上均显示出显著效果，如下所示：IBS-SSS 治疗前（M=272.0，SD=75.5）；IBS-SSS 治疗后（M=177.0，SD=103.5）；GSRS-IBS 治疗前（M=48.4，SD=15.9）；GSRS-IBS 治疗后（M=37.4，SD=12.4）；VSI 治疗前（M=38.8，SD=10.0）；VSI 治疗后（M=25.9，SD=10.1）；PHQ12 治疗前（M=10.0，SD=4.3）；PHQ12 治疗后（M=6.9，SD=4.3）；HADS 焦虑治疗前（M=8.9，SD=5.0）；HADS 焦虑治疗后（M=5.7，SD=3.3）；HADS 抑郁治疗前（M=5.6，SD=3.2）；HADS 抑郁治疗后（M=3.8，SD=2.9）；IBS-QOL 治疗前（M=64.5，SD=12.5）；IBS-QOL 治疗后（M=72.3，SD=10.0）。除一般焦虑和抑郁外，治疗后的效果可维持至随访期。治疗 3 个月时的初步效果在主要结局方面处于中到大的范围。
为期 10 周的团体阿斯汤加干预措施对 IBS 患者来说是一种可行的干预措施。初步效果令人鼓舞，应在随机试验中进一步探索。
