Eastin Ella F, Tiwari Anushri, Quach Tom C, Bonilla Hector F, Miglis Mitchell G, Yang Phillip C, Geng Linda N
Medicine, Stanford University School of Medicine, Palo Alto, USA.
Medicine, Stanford University, Palo Alto, USA.
Cureus. 2023 Dec 29;15(12):e51286. doi: 10.7759/cureus.51286. eCollection 2023 Dec.
Post-acute sequelae of SARS-CoV-2 (PASC), or long COVID, is characterized by persistent symptoms after acute SARS-CoV-2 infection that can vary from patient to patient. Here, we present a case series of four patients with a history of SARS-CoV-2 infection referred to the Post-Acute COVID-19 Syndrome (PACS) Clinic at Stanford University for evaluation of persistent symptoms, who also experienced new-onset alcohol sensitivity. Alcohol reactions and sensitivity are not well characterized in the literature as it relates to post-viral illness. While there have been some anecdotal reports of new alcohol sensitivity in PASC patients in the media, there is a paucity of published data in the medical literature about this topic. During their medical consultation, the patients self-reported new changes in their symptoms or behaviors following the use of alcohol. A new onset of alcohol sensitivities should be assessed along with other post-COVID-19 symptoms and may provide novel avenues to explore the pathobiology of illness and potential interventions.
2019冠状病毒病急性后遗症（PASC），即长期新冠症状，其特征是急性2019冠状病毒病感染后持续出现症状，症状因患者而异。在此，我们报告了一系列4例有2019冠状病毒病感染史的病例，这些患者因持续症状被转诊至斯坦福大学的急性新冠后综合征（PACS）诊所进行评估，他们还出现了新发酒精敏感性。酒精反应和敏感性在与病毒感染后疾病相关的文献中尚无明确描述。虽然媒体上有一些关于PASC患者出现新发酒精敏感性的轶事报道，但医学文献中关于这一主题的已发表数据很少。在医疗咨询过程中，患者自述饮酒后症状或行为出现了新变化。新发酒精敏感性应与其他新冠后症状一起评估，这可能为探索疾病的病理生物学和潜在干预措施提供新途径。
