Onimaru H, Homma I
Brain Res. 1987 Feb 17;403(2):380-4. doi: 10.1016/0006-8993(87)90080-1.
Rhythmic neuronal activity preceding C4 inspiratory activity (Pre-I neuron activity) was recorded in rostral ventrolateral (near ventral surface) medulla of brainstem-spinal cord preparation isolated from newborn rat. Vagal stimulation inhibited C4 activity but not Pre-I neuron activity. Rhythmic Pre-I neuron-like activity was still recorded in the block of rostral medulla after transection. Results suggest that Pre-I neurons generate the basic respiratory rhythm and trigger inspiratory activity.
在从新生大鼠分离的脑干脊髓标本的延髓腹外侧（靠近腹面）记录到了先于C4吸气活动的节律性神经元活动（吸气前神经元活动）。迷走神经刺激抑制了C4活动，但未抑制吸气前神经元活动。横断后，在延髓头端的阻断部位仍记录到节律性的类似吸气前神经元的活动。结果表明，吸气前神经元产生基本呼吸节律并触发吸气活动。
