Sloper J J, Headon M P, Powell T P
Brain Res. 1987 Feb;428(2):267-76. doi: 10.1016/0165-3806(87)90124-6.
Cell areas have been measured in the monocular segment of the lateral geniculate nucleus in a series of 18 normal rhesus monkeys and in 27 following monocular or binocular lid closure or monocular enucleation. Cells in the parvocellular monocular segment shrank by 16% during the later period of normal development, between about 3 and 18 months of age, in contrasts to cells in the binocular segment which did not. Monocular closure at birth caused hypertrophy of cells in the undeprived monocular segment whereas long-term closure started later caused shrinkage of both deprived and undeprived parvocellular cells additional to that occurring during normal development. In both these instances cells in the monocular segment related to the undeprived eye are undergoing changes indicating some form of binocular interactions even in the monocular segment, but these interactions are considerably weaker than in the binocular part of the nucleus. Enucleation caused marked transneuronal degeneration of cells in the contralateral monocular segment of both infant and adult monkeys.
在一系列18只正常恒河猴以及27只经历单眼或双眼眼睑闭合或单眼摘除的恒河猴中，对外侧膝状核单眼段的细胞面积进行了测量。在正常发育后期，即大约3至18个月大时，小细胞单眼段的细胞缩小了16%，而双眼段的细胞则没有。出生时单眼闭合会导致未受剥夺单眼段的细胞肥大，而后期开始的长期闭合除了正常发育期间发生的情况外，还会导致受剥夺和未受剥夺的小细胞均出现萎缩。在这两种情况下，与未受剥夺眼相关的单眼段细胞都在发生变化，这表明即使在单眼段也存在某种形式的双眼相互作用，但这些相互作用比核的双眼部分要弱得多。摘除眼球会导致幼年和成年猴子对侧单眼段的细胞发生明显的跨神经元变性。
