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不同年龄摘除眼球对幼年和成年猴子外侧膝状核中神经元大小的影响。

Effects of enucleation at different ages on the sizes of neurons in the lateral geniculate nucleus of infant and adult monkeys.

作者信息

Sloper J J, Headon M P, Powell T P

出版信息

Brain Res. 1987 Feb;428(2):259-65. doi: 10.1016/0165-3806(87)90123-4.

DOI:10.1016/0165-3806(87)90123-4
PMID:3828833
Abstract

Cell areas have been measured in the lateral geniculate nucleus following enucleation in 7 infant and 3 adult monkeys. Deafferented cells showed rapid transneuronal degeneration. Following enucleation at birth non-deafferented parvocellular LGN cells underwent hypertrophy which was followed by a delayed return to normal size. Enucleation at 7 months of age caused marked shrinkage of non-deafferented parvocellular cells. These changes in the non-deafferented cells are similar to those following monocular lid closure at the same ages. Sizes of non-deafferented cells were unchanged following enucleation of adult monkeys.

摘要

在7只幼年和3只成年猴子摘除眼球后,对其外侧膝状核中的细胞区域进行了测量。去传入神经的细胞表现出快速的跨神经元变性。出生时摘除眼球后,未去传入神经的小细胞外侧膝状核细胞会发生肥大,随后延迟恢复到正常大小。7个月大时摘除眼球会导致未去传入神经的小细胞明显萎缩。这些未去传入神经细胞的变化与相同年龄单眼眼睑闭合后的变化相似。成年猴子摘除眼球后,未去传入神经细胞的大小没有变化。

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Effects of enucleation at different ages on the sizes of neurons in the lateral geniculate nucleus of infant and adult monkeys.不同年龄摘除眼球对幼年和成年猴子外侧膝状核中神经元大小的影响。
Brain Res. 1987 Feb;428(2):259-65. doi: 10.1016/0165-3806(87)90123-4.
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