Division of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, Korea.
Department of Internal Medicine, Seoul National College of Medicine, Seoul, Korea.
J Korean Med Sci. 2024 Jan 29;39(4):e19. doi: 10.3346/jkms.2024.39.e19.
Mpox is a viral illness with a characteristic skin rash caused by the monkeypox virus. In 2022, Mpox spread throughout the world, and an epidemic through domestic transmission started in South Korea in early 2023. This study aimed to summarize the clinical features of Mpox patients in South Korea.
This is a multicenter retrospective study conducted at four hospitals in South Korea. All adult patients diagnosed with Mpox who were admitted to the study hospitals between June 1, 2022 and May 26, 2023 and were discharged by June 30, 2023 were reviewed.
Sixty patients were included, accounting for 65.9% of Mpox cases reported in South Korea during the study period. Median age was 32 years and 97% (58/60) of patients were male. In total, 85% (51/60) of patients reported their sexual orientation as homosexual or bisexual. The most common route of transmission was sexual or close contact (55/60). Every patient had a skin rash and 88% (53/60) had constitutional symptoms. In total, 42% (25/60) of patients had human immunodeficiency virus and 25% (15/60) had concomitant sexually transmitted infections. Severe manifestations of Mpox were identified in only two patients.
Mpox patients in South Korea were mainly young adult males and were infected through sexual contact. The clinical outcomes were favorable.
猴痘是一种病毒性疾病，由猴痘病毒引起，其特征性皮疹。2022 年，猴痘在全球范围内传播，2023 年初韩国开始发生国内传播的疫情。本研究旨在总结韩国猴痘患者的临床特征。
这是一项在韩国四家医院进行的多中心回顾性研究。纳入 2022 年 6 月 1 日至 2023 年 5 月 26 日期间在研究医院住院并于 2023 年 6 月 30 日前出院的确诊为猴痘的所有成年患者。
共纳入 60 例患者，占研究期间韩国报告的猴痘病例的 65.9%。中位年龄为 32 岁，97%（58/60）的患者为男性。共有 85%（51/60）的患者报告其性取向为同性恋或双性恋。最常见的传播途径是性接触或密切接触（55/60）。所有患者均有皮疹，88%（53/60）有全身症状。共有 42%（25/60）的患者感染了人类免疫缺陷病毒，25%（15/60）的患者合并性传播感染。仅两名患者出现猴痘的严重表现。
韩国的猴痘患者主要为年轻成年男性，通过性接触感染。临床结局良好。
