National Health and Medical Research Council Centre for Research Excellence in Severe Asthma, University of Newcastle, Newcastle, New South Wales, Australia; National Health and Medical Research Council Centre for Research Excellence in Treatable Traits, Hunter Medical Research Institute Asthma and Breathing Research Program, Newcastle, New South Wales, Australia; School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia.
National Health and Medical Research Council Centre for Research Excellence in Treatable Traits, Hunter Medical Research Institute Asthma and Breathing Research Program, Newcastle, New South Wales, Australia; Speech Pathology Department, John Hunter Hospital, New Lambton Heights, New South Wales, Australia; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.
J Allergy Clin Immunol Pract. 2024 May;12(5):1326-1336. doi: 10.1016/j.jaip.2024.01.028. Epub 2024 Jan 28.
Asthma and vocal cord dysfunction (VCD), also known as inducible laryngeal obstruction (ILO), may coexist, resulting in worse outcomes for patients. The experience of people with VCD/ILO and coexisting asthma is unknown.
We sought to determine whether coexistent VCD/ILO and asthma have deleterious impacts on quality of life.
We undertook a descriptive qualitative study using one-to-one semistructured interviews with 30 purposively recruited adult participants with a prior confirmed doctor asthma diagnosis and laryngoscopy-confirmed VCD/ILO. A thematic and content analysis was conducted to explore the data.
Participants were mostly female (63%), mean ± SD age 63 ± 12 years. Four themes were identified: trapped voice, altered life, knowledge about VCD/ILO, and looking for solutions. Participants reported their voice being trapped in their throat or the voice being suddenly cut off when talking or singing. Self-reported VCD/ILO symptoms including throat tightness and breathlessness were highlighted by participants. The second theme described how patients struggle to communicate or tended to shorten conversations. Insufficient knowledge and existing confusion regarding whether asthma was causing the breathlessness was described in the third theme. Looking for solutions depicted participants' diagnostic journey and how they sought an explanation for the symptoms.
People with asthma and coexisting VCD/ILO experience a substantial burden affecting the quality of life. These data describe the impact on patients with coexisting conditions and should be used to increase clinician awareness of the experience of VCD/ILO from patients' perspectives to support a personalized approach to care.
哮喘和声带功能障碍（VCD），也称为可诱导性喉阻塞（ILO），可能同时存在，导致患者的预后更差。同时患有 VCD/ILO 和哮喘的患者的体验尚不清楚。
我们旨在确定同时存在的 VCD/ILO 和哮喘是否对生活质量有不良影响。
我们采用描述性定性研究方法，对 30 名经医生确诊哮喘和喉镜确诊 VCD/ILO 的成年参与者进行了一对一的半结构化访谈。采用主题和内容分析法对数据进行了分析。
参与者主要为女性（63%），平均年龄±标准差为 63±12 岁。确定了四个主题：被困住的声音、改变的生活、关于 VCD/ILO 的知识和寻找解决方案。参与者报告说，他们的声音被困在喉咙里，或者在说话或唱歌时声音突然中断。参与者强调了自我报告的 VCD/ILO 症状，包括喉咙发紧和呼吸困难。第二个主题描述了患者在交流方面的困难，以及他们倾向于缩短对话。第三个主题描述了患者对哮喘是否导致呼吸困难的知识不足和现有困惑。寻找解决方案描述了参与者的诊断过程，以及他们如何为症状寻找解释。
同时患有哮喘和 VCD/ILO 的人会经历严重的生活质量负担。这些数据描述了同时患有这两种疾病的患者的影响，应该用于提高临床医生对 VCD/ILO 从患者角度的体验的认识，以支持个性化的护理方法。
