Mammana Marco, Verzeletti Vincenzo, Baldi Matteo, Schiavon Marco, Dell'Amore Andrea, Rea Federico
Thoracic Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Eur J Cardiothorac Surg. 2024 Feb 1;65(2). doi: 10.1093/ejcts/ezae026.
Benign (laryngo-)tracheal stenosis is a relatively rare pathology and its surgical treatment is performed only at few specialized centres. This study aims to investigate outcomes after (laryngo-)tracheal resection-anastomosis, to explore potential risk factors for postoperative complications and to assess whether, over a 33-year period, there were major changes in surgical indications, techniques or outcomes.
Retrospective, single-centre review of all consecutive patients who underwent tracheal or laryngo-tracheal resection/anastomosis for benign pathologies from 1990 to 2023.
Overall, 211 patients underwent tracheal (149 patients, 70.6%) and laryngo-tracheal (62 patients, 29.4%) resection-anastomosis. Of these, 195 patients (93.8%) were affected by iatrogenic stenosis, while 13 (6.2%) suffered from idiopathic stenosis. The median length of stenosis was 25 mm (interquartile range 1-3, 20-30). The overall morbidity rate was 27.5%, while major morbidity occurred in 10.5% of cases. One patient (0.5%) died in the postoperative period. Glottic oedema (17 patients, 8.1%), granulations (12 patients, 5.7%) and restenosis (10 patients, 4.7%) were the main complications. The only independent risk factor for postoperative complications was the length of the resected airway (P = 0.019). In the latest half of the study period, an older median age was observed, and no patient with idiopathic tracheal stenosis underwent surgery. Postoperative outcomes were comparable between surgical eras.
Surgical treatment of (laryngo-)tracheal stenosis is challenging and should be performed by specialized centres. In our experience, morbidity and mortality rates were satisfactory, and in most cases, patients could breathe without tracheostomy. The length of the stenosis was the most significant risk factor for postoperative complications.
良性(喉)气管狭窄是一种相对罕见的病理情况,其手术治疗仅在少数专业中心开展。本研究旨在调查(喉)气管切除吻合术后的结果,探索术后并发症的潜在风险因素,并评估在33年期间手术适应证、技术或结果是否有重大变化。
对1990年至2023年因良性病变接受气管或喉气管切除/吻合术的所有连续患者进行单中心回顾性研究。
总体而言,211例患者接受了气管切除吻合术(149例患者,占70.6%)和喉气管切除吻合术(62例患者,占29.4%)。其中,195例患者(93.8%)患有医源性狭窄,而13例(6.2%)患有特发性狭窄。狭窄的中位长度为25毫米(四分位间距1 - 3,20 - 30)。总体发病率为27.5%,而严重发病率为10.5%。1例患者(0.5%)在术后死亡。声门水肿(17例患者,占8.1%)、肉芽组织增生(12例患者,占5.7%)和再狭窄(10例患者,占4.7%)是主要并发症。术后并发症的唯一独立风险因素是切除气道的长度(P = 0.019)。在研究期的后半段,观察到中位年龄较大,且没有特发性气管狭窄患者接受手术。不同手术时期的术后结果具有可比性。
(喉)气管狭窄的手术治疗具有挑战性,应由专业中心进行。根据我们的经验,发病率和死亡率令人满意,在大多数情况下,患者无需气管造口即可呼吸。狭窄长度是术后并发症最显著的风险因素。