Hahnfeldt K R, Breinl H F
Clin Ther. 1986;9 Suppl A:22-5.
Microbiologic diagnostic tests (comprising phase-contrast microscopy, fungal cultures, staining cytology, and immunofluorescence microscopy with monoclonal antibodies against Chlamydia trachomatis) were performed in 100 women with recurrent urogenital infections. The incidence and localization of Chlamydia trachomatis are reported. The therapeutic efficacy of systemic treatment with doxycycline in this group was evaluated. All of the 25 patients in whom treatment and treatment results could be supervised reported marked or complete relief of symptoms after ten days of treatment with 200 mg/day of doxycycline. All clinical findings were normal, and immunofluorescence microscopy showed that the microorganisms were eradicated in all patients. Doxycycline was well tolerated, with only two patients reporting mild abdominal pain, which did not require termination of treatment.
对100名复发性泌尿生殖系统感染的女性进行了微生物诊断测试(包括相差显微镜检查、真菌培养、染色细胞学检查以及使用抗沙眼衣原体单克隆抗体的免疫荧光显微镜检查)。报告了沙眼衣原体的发病率和感染部位。评估了该组患者使用强力霉素进行全身治疗的疗效。在25名能够监测治疗及治疗结果的患者中,所有患者在接受200毫克/天强力霉素治疗10天后均报告症状明显缓解或完全缓解。所有临床检查结果均正常,免疫荧光显微镜检查显示所有患者体内的微生物均已根除。强力霉素耐受性良好,只有两名患者报告有轻微腹痛,无需终止治疗。