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超声引导下射频消融治疗胆囊息肉的安全性和有效性。

Safety and Efficacy of Ultrasound-Guided Radiofrequency Ablation in the Treatment of Gallbladder Polyps.

机构信息

Department of Ultrasound, the First Affiliated Hospital of Zhengzhou University, Jianshe Dong Road, ErQi District, Zhengzhou, China.

Department of Ultrasound, the First Affiliated Hospital of Zhengzhou University, Jianshe Dong Road, ErQi District, Zhengzhou, China.

出版信息

Acad Radiol. 2024 Aug;31(8):3157-3164. doi: 10.1016/j.acra.2024.01.016. Epub 2024 Jan 29.

Abstract

RATIONALE AND OBJECTIVES

To investigate the safety and efficacy of ultrasound-guided radiofrequency ablation (RFA) in the treatment of gallbladder polyps.

MATERIALS AND METHODS

A retrospective analysis was conducted on the medical records of 296 patients diagnosed with gallbladder polyps. The study observed the changes in lesions post-procedure within the ablation group, and compared whether there was a difference in the gallbladder contraction rate in patients before and after ablation. It also compared the liver function indicators before and after surgery, some indicators during the periprocedural period, and the incidence of complications in two groups of patients.

RESULTS

In the ablation group, all lesions (84/84) were completely ablated, and the absorption effect of the ablation lesions was good after the ablation. No significant differences were observed in the gallbladder contraction rate before ablation compared to 1 month and 3 months post-ablation (p > 0.05). After the operation, statistically significant differences were observed in ALT and TP between the two groups (all p < 0.05). Significant differences were observed between the two groups in terms of hospital stay, procedural time, postprocedural mobilization time, postprocedural exhaust time, postprocedural eating time, and VAS score on postprocedural day 3 (all p < 0.05). There was no significant difference in the incidence of complications between the two groups (x=0.477,p = 0.490).

CONCLUSION

Our findings demonstrate that ultrasound-guided RFA is a safe, effective, and feasible treatment for gallbladder polyps, as it not only effectively eliminates the polyps but also preserves the physiological functions of the gallbladder.

摘要

目的

研究超声引导下射频消融(RFA)治疗胆囊息肉的安全性和有效性。

材料和方法

对 296 例经超声诊断为胆囊息肉的患者的病历进行回顾性分析。观察消融组术后病变的变化,并比较消融前后患者胆囊收缩率的差异。还比较了两组患者手术前后的肝功能指标、围手术期的一些指标以及并发症的发生率。

结果

在消融组中,所有病变(84/84)均完全消融,消融后消融病变的吸收效果良好。消融前与消融后 1 个月和 3 个月的胆囊收缩率无显著差异(p>0.05)。术后两组间 ALT 和 TP 有统计学差异(均 p<0.05)。两组在住院时间、手术时间、术后活动时间、术后排气时间、术后进食时间和术后 3 天 VAS 评分方面有显著差异(均 p<0.05)。两组并发症发生率无显著差异(x=0.477,p=0.490)。

结论

超声引导下 RFA 治疗胆囊息肉安全、有效、可行,不仅能有效消除息肉,还能保留胆囊的生理功能。

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