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头颈部癌症并发症:颈动脉破裂综合征。

Complication of head and neck cancer: Carotid blowout syndrome.

机构信息

University of Missouri, School of Medicine, United States of America.

University of Missouri, School of Medicine, United States of America.

出版信息

Am J Emerg Med. 2024 Mar;77:231.e5-231.e6. doi: 10.1016/j.ajem.2024.01.025. Epub 2024 Jan 24.

Abstract

Carotid blowout syndrome (CBS) is an uncommon but potentially life-threatening condition characterized by the spontaneous or traumatic rupture of the carotid artery in the neck. Oftentimes, CBS is due a loss of structural arterial integrity from local radiotherapy or surgical procedures. A vast majority of patients who develop CBS also have a previous diagnosis of head and neck cancer. Due to the specific patient population who develop CBS and its life-threatening nature, CBS should be a part of emergency physicians differential for those who present with a chronic neck wound or neurological symptoms in those with a previous head and neck cancer diagnosis. In this case report, a patient with a history of squamous cell carcinoma of the oropharynx who was treated with chemoradiation therapy, presented to the emergency department with spontaneous bleeding from an existing chronic wound on the left lateral neck. Conservative measures were taken including wound dressing, and the patient was discharged to see dermatology for biopsy of a suspected cancerous lesion. Once the chronic lesion was biopsied, the patient had to be immediately rushed to the operating room due to a brisk pulsatile bleeding from puncturing the carotid artery. Proper wound packing and an ultrasound of the neck for a proper diagnosis may have prevented the need for surgical intervention in this case. Although CBS is not common, complications can lead to death as seen in this case. Timely recognition and proper interventions are critical for preventing potentially fatal outcomes in those with CBS.

摘要

颈动脉破裂综合征(CBS)是一种不常见但可能危及生命的疾病,其特征是颈部颈动脉自发性或外伤性破裂。CBS 通常是由于局部放疗或手术导致动脉结构完整性丧失。绝大多数发生 CBS 的患者也有头颈部癌症的既往诊断。由于发生 CBS 的患者人群特定且其具有致命性,对于那些有慢性颈部伤口或有头颈部癌症既往诊断的出现神经症状的患者,CBS 应成为急诊医生鉴别诊断的一部分。在本病例报告中,一名患有口咽鳞状细胞癌的患者接受了放化疗治疗,因左侧颈部现有慢性伤口自发性出血而到急诊就诊。采用了保守治疗措施,包括伤口包扎,并将患者出院至皮肤科进行疑似癌变病灶的活检。一旦对慢性病变进行了活检,由于颈动脉刺穿后出现快速搏动性出血,患者必须立即被送往手术室。如果对适当的伤口进行包扎并对颈部进行超声检查以做出正确诊断,本病例可能无需手术干预。尽管 CBS 并不常见,但并发症可导致死亡,如本病例所见。及时识别和适当干预对于预防 CBS 患者潜在致命后果至关重要。

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