Department of Physical Examination Center, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Department of Ultrasound in Obstetrics and Gynecology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
BMC Pregnancy Childbirth. 2024 Jan 30;24(1):92. doi: 10.1186/s12884-024-06279-4.
The appropriate use of obstetric blood transfusion is crucial for patients with placenta previa and prenatal anemia. This retrospective study aims to explore the correlation between prenatal anemia and blood transfusion-related parameters in this population.
We retrieved the medical records of consecutive participants who were diagnosed with placenta previa and underwent cesarean section in our hospital. We compared the baseline demographics and clinical characteristics of patients with and without anemia. The correlation between prenatal anemia and obstetric blood transfusion-related parameters was evaluated using multivariate regression analysis.
A total of 749 patients were enrolled, with a mean prenatal hemoglobin level of 10.87 ± 1.37 g/dL. Among them, 54.87% (391/749) were diagnosed with anemia. The rate of obstetric blood transfusion was significantly higher in the anemia group (79.54%) compared to the normal group (44.41%). The median allogeneic red blood cell transfusion volume in the anemia group was 4.00 U (IQR 2.00-6.00), while in the normal group, it was 0.00 U (IQR 0.00-4.00). The prenatal hemoglobin levels had a non-linear relationship with intraoperative allogeneic blood transfusion rate, massive blood transfusion rate, red blood cell transfusion units, and fresh plasma transfusion volume in patients with placenta previa, with a threshold of 12 g/dL.
Our findings suggest that prenatal anemia is associated with a higher rate of blood transfusion-related parameters in women with placenta previa when the hemoglobin level is < 12 g/dL. These results highlight the importance of promoting prenatal care in placenta previa patients with a high requirement for blood transfusion.
前置胎盘伴产前贫血患者的产科输血合理应用至关重要。本回顾性研究旨在探讨该人群中产前贫血与输血相关参数的相关性。
我们检索了在我院因前置胎盘行剖宫产术的连续患者的病历资料。比较了贫血组和非贫血组患者的基线人口统计学和临床特征。采用多元回归分析评估产前贫血与产科输血相关参数的相关性。
共纳入 749 例患者，产前血红蛋白水平平均为 10.87±1.37 g/dL。其中，54.87%（391/749）诊断为贫血。贫血组的产科输血率明显高于正常组（79.54%比 44.41%）。贫血组异体红细胞输注中位数为 4.00 U（IQR 2.00-6.00），正常组为 0.00 U（IQR 0.00-4.00）。产前血红蛋白水平与前置胎盘患者术中异体输血率、大量输血率、红细胞输注单位和新鲜血浆输注量呈非线性关系，阈值为 12 g/dL。
本研究结果表明，当血红蛋白水平<12 g/dL 时，前置胎盘患者产前贫血与输血相关参数的发生率较高。这些结果强调了在前置胎盘患者中促进产前保健以满足高输血需求的重要性。
