Talaway Athalia Anastasia, Hidayati Hanik Badriyah
Department of Neurology, Neurology, Airlangga University Faculty of Medicine, Dr. Soetomo General Hospital, Mayjend Prof. Dr., Moestopo No. 6 - 8, Surabaya-60264, Surabaya-Indonesia.
Radiol Case Rep. 2024 Jan 13;19(4):1271-1275. doi: 10.1016/j.radcr.2023.12.042. eCollection 2024 Apr.
Vestibular Schwannoma (VS) is a benign nerve sheath tumors comprised of Schwann cells. This tumor is encapsulated, slow-growing, and originates from the internal auditory canal, extending into the cerebellopontine angle (CPA). The incidence in individuals aged 20-44 is 0.75 per 100,000 cases, with bilateral VS incidence of 0.8 per 50,000 cases. Tumors in CPA are the most common type in the posterior fossa and cause serious neurological symptoms or become life-threatening when tumors enlarge and compress the brainstem. The majority of tumors are VS (acoustic neuromas), accounting for 80%-90% of cases. Common clinical symptoms include hearing loss, tinnitus, and vertigo. Additionally, these tumors cause compression of the trigeminal and facial nerves. Advances in rapidly evolving imaging technology and surgical methods have improved diagnosis and management. A 24-year-old male complained of hearing impairment for the past 3 years alongside headaches, and dizziness leading to a feeling of imbalance, double, and blurry vision, as well as a sensation of facial thickness on the left side. Neurological examination showed cranial nerve abnormalities, including bilateral paresis of cranial nerves III, IV, VI, left cranial nerves V and VII, bilateral cranial nerve VIII, right cranial nerve XII, and cerebellar abnormalities such as intention tremor, dysmetria, dysdiadokokinesia, wide-based gait, and falling to the right during Romberg testing with both eyes open and closed. The patient underwent a contrast-enhanced MRI of the head, followed by a right CPA tumors excision through craniotomy. A detailed understanding of the medical history, physical examination, and radiological proved to be crucial in establishing an accurate diagnosis and appropriate management. This was considered essential to minimize a worse prognosis.
前庭神经鞘瘤(VS)是一种由施万细胞组成的良性神经鞘瘤。该肿瘤有包膜,生长缓慢,起源于内耳道,延伸至桥小脑角(CPA)。20 - 44岁人群的发病率为每10万例中有0.75例,双侧VS发病率为每5万例中有0.8例。CPA肿瘤是后颅窝最常见的类型,当肿瘤增大并压迫脑干时会引起严重的神经症状或危及生命。大多数肿瘤为VS(听神经瘤),占病例的80% - 90%。常见临床症状包括听力丧失、耳鸣和眩晕。此外,这些肿瘤会压迫三叉神经和面神经。快速发展的成像技术和手术方法的进步改善了诊断和治疗。一名24岁男性在过去3年中出现听力障碍,伴有头痛、头晕,导致失衡感、复视和视力模糊,以及左侧面部增厚感。神经检查显示颅神经异常,包括双侧动眼神经、滑车神经、展神经麻痹,左侧三叉神经和面神经麻痹,双侧位听神经、右侧舌下神经麻痹,以及小脑异常,如意向性震颤、辨距不良、轮替运动障碍、宽基底步态,睁眼和闭眼时Romberg试验均向右倾倒。患者接受了头部增强MRI检查,随后通过开颅手术切除了右侧CPA肿瘤。详细了解病史、体格检查和影像学检查对于准确诊断和适当治疗至关重要。这被认为是将预后恶化降至最低的关键。