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婴儿型胎儿样腹部肿块:畸胎瘤还是胎中胎?一例病例报告及对放射学诊断和手术治疗的见解

Infantile fetiform abdominal mass: Teratoma or fetus in fetu? A case report with insights into radiological diagnosis and surgical management.

作者信息

Sharma Jitendra, Yadav Upasna, Tej Varun, Malik Rajesh, Sarawagi Radha, Rahman Nadeem, Kumar Aman, Patel Ankur, Bhagat Abhinav C

机构信息

Department of Radiodiagnosis, AIIMS Bhopal, Bhopal, Madhya Pradesh, India.

出版信息

Radiol Case Rep. 2024 Jan 13;19(4):1304-1308. doi: 10.1016/j.radcr.2023.12.031. eCollection 2024 Apr.

DOI:10.1016/j.radcr.2023.12.031
PMID:38292806
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10825550/
Abstract

Fetus-in-fetu (FIF) is a rare congenital anomaly in which a malformed parasitic twin develops within the body of a live fetus or child. Abdominal teratoma, a type of germ cell tumor, can be a great imaging mimicker of FIF and vice-versa, as they both can present as a heterogeneous mass with calcifications and a fat component. Radiological differentiation of these 2 entities should be made because of the difference in surgical planning and treatment options. Features such as visualization of distinct bony vertebral elements and encysted cystic components are the specific features of Fetus in fetu [1]. In contrast, the presence of elevated serum markers can help diagnose teratoma. Here, we report a case of a 5-month-old girl presented with progressive distension of the upper abdomen for the last 2 months, noticed by her mother. Her initial imaging with abdominal X-ray and ultrasonography showed the presence of a large heterogenous solid-cystic mass in the upper abdomen with large elongated calcifications. A provisional diagnosis of teratoma vs FIF was considered. CECT abdomen showed clear identification of osseous structures of the axial and appendicular skeleton within a fat density mass, along with an encapsulated cystic component, strongly suggestive of FIF. Her serum tumor markers were within normal limits. The final diagnosis of FIF was confirmed on Laparotomy and postoperative specimens.

摘要

胎内胎(FIF)是一种罕见的先天性异常,其中一个畸形的寄生双胞胎在活胎儿或儿童体内发育。腹部畸胎瘤是一种生殖细胞肿瘤,可能在影像学上与胎内胎极为相似,反之亦然,因为它们都可表现为具有钙化和脂肪成分的异质性肿块。由于手术规划和治疗方案不同,应对这两种病变进行影像学鉴别。诸如可见明显的骨性脊椎结构和包囊性囊性成分等特征是胎内胎的特异性表现[1]。相比之下,血清标志物升高有助于诊断畸胎瘤。在此,我们报告一例5个月大女童的病例,其母亲注意到她在过去2个月中上腹逐渐膨隆。她最初的腹部X线和超声检查显示上腹部存在一个大的异质性实性-囊性肿块,伴有粗大的长条状钙化。考虑初步诊断为畸胎瘤与胎内胎。腹部增强CT显示在一个脂肪密度肿块内清晰识别出轴骨和附属骨骼的骨性结构,以及一个包囊性囊性成分,强烈提示为胎内胎。她的血清肿瘤标志物在正常范围内。剖腹手术及术后标本证实了胎内胎的最终诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f4/10825550/98c00ef80bab/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f4/10825550/9bf01b1dbf00/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f4/10825550/549ee4b3e05e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f4/10825550/063bd4109c08/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f4/10825550/61a52e01c478/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f4/10825550/98c00ef80bab/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f4/10825550/9bf01b1dbf00/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f4/10825550/549ee4b3e05e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f4/10825550/063bd4109c08/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f4/10825550/61a52e01c478/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f4/10825550/98c00ef80bab/gr5.jpg

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本文引用的文献

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Cureus. 2023 Jan 12;15(1):e33725. doi: 10.7759/cureus.33725. eCollection 2023 Jan.
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