Mayo W, Leighton K, Robertson B, Ruedy J
Can J Anaesth. 1987 Jan;34(1):79-82. doi: 10.1007/BF03007692.
Intraoperative cyanosis is most commonly caused by hypoxaemia. The anaesthetist is required to perform a rapid series of diagnostic manoeuvres and take remedial action. Occasionally methaemoglobin, sulfhaemoglobin, or haemoglobin M, undetected preoperatively, is the cause of the cyanosis. We report a case of methaemoglobinaemia secondary to dapsone ingestion that was diagnosed intraoperatively. Dapsone, a sulfone, is used therapeutically to treat leprosy and dermatitis herpetiformis. The differential diagnosis of cyanosis, and the origin and fate of methaemoglobin are discussed. In addition the diagnostic steps and the laboratory investigations required to make the diagnosis are listed.
术中发绀最常见的原因是低氧血症。麻醉医生需要迅速进行一系列诊断操作并采取补救措施。偶尔，术前未检测到的高铁血红蛋白、硫血红蛋白或血红蛋白M是发绀的原因。我们报告一例术中诊断为因服用氨苯砜继发高铁血红蛋白血症的病例。氨苯砜是一种砜类药物，用于麻风病和疱疹样皮炎的治疗。本文讨论了发绀的鉴别诊断以及高铁血红蛋白的来源和转归。此外，还列出了做出诊断所需的诊断步骤和实验室检查。
