检测乙酰胆碱酯酶和丁酰胆碱酯酶 使用一种新的荧光探针。
Detection of acetylcholinesterase and butyrylcholinesterase and using a new fluorescent probe.
机构信息
Shaanxi Engineering Laboratory for Food Green Processing and safety Control, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710062, China.
出版信息
Chem Commun (Camb). 2024 Feb 15;60(15):2082-2085. doi: 10.1039/d3cc06055a.
A new fluorescence probe OHPD that could specifically identify acetylcholinesterase/butyrylcholinesterase has been developed and successfully applied to imaging . Probe OHPD shows significant color change, high selectivity, high sensitivity, and low detection limit for the detection of cholinesterase. Moreover, the real-time imaging indicated that endogenous cholinesterase was mainly present in the yolk sac of zebrafish.
一种新的荧光探针 OHPD 已经被开发出来，可以特异性识别乙酰胆碱酯酶/丁酰胆碱酯酶，并成功应用于成像。探针 OHPD 对胆碱酯酶的检测表现出显著的颜色变化、高选择性、高灵敏度和低检测限。此外，实时成像表明内源性胆碱酯酶主要存在于斑马鱼的卵黄囊中。
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