Peng Xuepei, Guo Xingtong, Zhou Yuwen
School of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Department of Stomatology, Jiaxing Maternal and Child Health Hospital, Jiaxing, China.
Photobiomodul Photomed Laser Surg. 2024 Feb;42(2):99-124. doi: 10.1089/photob.2023.0109. Epub 2024 Jan 31.
This study aimed to evaluate the impact of 10 adjunctive measures on non-surgical therapy outcomes for peri-implant disease. We formulated the study question and keywords following the Population, Intervention, Comparator, Outcome framework. Randomized controlled trials were identified through searches in PubMed, Embase, the Cochrane Library, and the Web of Science. Two researchers assessed the quality of included literature according to the Cochrane Risk of Bias Assessment Tool. Data analysis and ranking were performed using Stata 15.0 software. This study, involving 51 pieces of literature and 2660 samples, conducted a network meta-analysis (NMA), which revealed that photodynamic therapy (PDT) significantly reduced probing pocket depth values in patients with peri-implant mucositis (SUCRA = 96.3%) and peri-implantitis (SUCRA = 96.7%). In addition, it showed an improvement in bleeding on probing (BOP) values for peri-implantitis (SUCRA = 91.6%). Furthermore, diode lasers improved BOP values for peri-implant mucositis (SUCRA = 76.5%). According to the NMA results and the surface under the cumulative ranking curve (SUCRA), PDT and diode laser outperform other adjuncts in peri-implant disease.
本研究旨在评估10种辅助措施对种植体周围疾病非手术治疗效果的影响。我们按照人群、干预措施、对照、结局框架制定了研究问题和关键词。通过检索PubMed、Embase、Cochrane图书馆和科学网来识别随机对照试验。两名研究人员根据Cochrane偏倚风险评估工具评估纳入文献的质量。使用Stata 15.0软件进行数据分析和排序。本研究纳入51篇文献和2660个样本，进行了网状Meta分析（NMA），结果显示光动力疗法（PDT）可显著降低种植体周围黏膜炎患者的探诊深度值（累积排序曲线下面积[SUCRA]=96.3%）和种植体周围炎患者的探诊深度值（SUCRA=96.7%）。此外，对于种植体周围炎，光动力疗法还可改善探诊出血（BOP）值（SUCRA=91.6%）。此外，二极管激光可改善种植体周围黏膜炎的BOP值（SUCRA=76.5%）。根据NMA结果和累积排序曲线下面积（SUCRA），在种植体周围疾病方面，光动力疗法和二极管激光优于其他辅助措施。
