Dental Department, Queen Sirikit National Institute of Child Health, Bangkok, Thailand.
Department of Paediatric Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Int J Paediatr Dent. 2024 Sep;34(5):630-638. doi: 10.1111/ipd.13163. Epub 2024 Jan 31.
Finding the best treatment approach and suitable capping materials in primary molars with deep carious lesions remains unresolved.
To compare the success rates of partial pulpotomy in deep caries lesions in primary molars treated with mineral trioxide aggregate (MTA), biodentine, or acemannan for 6-24 months.
A parallel-design, non-inferiority randomized controlled clinical trial was performed. Ninety mandibular primary molars from 65 children meeting the criteria, aged 3-8 years, were included. After inflamed pulp tissue removal and hemostasis, each tooth was randomly allocated into the MTA control group, or the biodentine or acemannan experimental group (N = 30 per group). All teeth were restored with a stainless steel crown. The outcomes were evaluated for 6-24 months. A generalized estimating equation model was used to compare the overall success rate in each group.
After 24 months, 58 children (83 teeth) were available for evaluation. The results indicated that the success rate in the MTA, biodentine, and acemannan groups was 83.3%, 76.9%, and 74.1%, respectively. No significant difference in success rates among groups, however, was observed at the 6- to 24-month follow-ups (at 24th month, p = .30).
There was no statistically significant difference between MTA, biodentine, or acemannan in the partial pulpotomy success after 24 months.
在深龋的乳磨牙中找到最佳的治疗方法和合适的盖髓材料仍然没有解决。
比较三氧化矿物聚合体（MTA）、生物陶瓷和甘露聚糖用于治疗深龋的乳磨牙部分活髓切断术 6-24 个月的成功率。
一项平行设计、非劣效性随机对照临床试验。纳入符合标准的 65 名 3-8 岁儿童的 90 颗下颌乳磨牙，将每个牙齿随机分配到 MTA 对照组或生物陶瓷或甘露聚糖实验组（每组 N=30）。所有牙齿均用不锈钢冠修复。在 6-24 个月时评估结果。使用广义估计方程模型比较每组的总体成功率。
24 个月后，58 名儿童（83 颗牙）可进行评估。结果表明，MTA、生物陶瓷和甘露聚糖组的成功率分别为 83.3%、76.9%和 74.1%。然而，在 6-24 个月的随访中，各组的成功率没有显著差异（在第 24 个月时，p=0.30）。
在 24 个月时，MTA、生物陶瓷和甘露聚糖在部分活髓切断术后的成功率没有统计学上的显著差异。
