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抗干扰素-γ自身抗体与沙门菌病:病例报告及文献综述

Anti-interferon-gamma autoantibody and salmonellosis: Case report and literature review.

作者信息

Towachiraporn Saikhuan, Thongwitokomarn Harit, Salee Parichat

机构信息

Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Thailand.

出版信息

IDCases. 2024 Jan 11;35:e01926. doi: 10.1016/j.idcr.2024.e01926. eCollection 2024.

Abstract

Adult-onset immunodeficiency syndrome is characterized by the presence of anti-interferon-gamma (IFN-γ) autoantibody and the distribution of infections. Here, we describe bacteremia in a Thai woman who also had anti-IFN-γ autoantibody. The patient was also suffering from osteomyelitis and a peri-orbital abscess. Her symptoms were completely eradicated after surgical intervention and the administration of appropriate antibiotics.

摘要

成人起病型免疫缺陷综合征的特征是存在抗干扰素-γ(IFN-γ)自身抗体以及感染的分布情况。在此,我们描述了一名泰国女性的菌血症病例,该患者也存在抗IFN-γ自身抗体。该患者还患有骨髓炎和眶周脓肿。经过手术干预和使用适当的抗生素后,她的症状完全消除。

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