INMA, Spanish National Research Council, University of Zaragoza, Zaragoza, Spain.
Instituto Universitario de Investigación en Envejecimiento, Universidad de Murcia, Murcia, Spain.
Ophthalmic Physiol Opt. 2024 Mar;44(2):334-346. doi: 10.1111/opo.13271. Epub 2024 Feb 1.
The intracapsular accommodation mechanism (IAM) may be understood as an increase in the lens equivalent refractive index as the eye accommodates. Our goal was to evaluate the existence of an IAM by analysing observed changes in the inner curvature gradient of the lens. To this end, we fitted a gradient index and curvature lens model to published experimental data on external and nucleus geometry changes during accommodation. For each case analysed, we computed the refractive power and equivalent index for each accommodative state using a ray transfer matrix. All data sets showed an increase in the effective refractive index, indicating a positive IAM, which was stronger for older lenses. These results suggest a strong dependence of the lens equivalent refractive index on the inner curvature gradient.
囊内适应机制(IAM)可以理解为眼睛调节时晶状体等效折射率的增加。我们的目标是通过分析晶状体内曲率梯度的观测变化来评估 IAM 的存在。为此,我们根据公布的关于调节过程中外层和核部几何形状变化的实验数据,拟合了梯度折射率和曲率透镜模型。对于分析的每种情况,我们使用射线传递矩阵计算了每个调节状态的屈光力和等效指数。所有数据集均显示出有效折射率的增加,表明存在正的 IAM,对于较老的晶状体,这种 IAM 更强。这些结果表明,晶状体等效折射率强烈依赖于内曲率梯度。