Konishi J, Iida Y, Kasagi K, Misaki T, Arai K, Endo K, Amemiya T, Abe M, Torizuka K
Endocrinol Jpn. 1986 Oct;33(5):637-44. doi: 10.1507/endocrj1954.33.637.
Seventeen patients with moderately severe ophthalmopathy due to Graves' disease were treated by cobalt or supervoltage radiotherapy. All patients complained of diplopia. The mean proptosis value was 21.4 mm. Three patients (18%) showed good response, 7 (41%) moderate and 7 minimal or no response. Improvement was noted mainly in soft tissue changes and diplopia, while proptosis decreased in only 5 patients. All except one patient who had marked extraocular muscle involvement revealed by computed tomography responded to treatment. These data indicate that radiotherapy may be indicated in patients with progressive ophthalmopathy, especially in those who are associated with extraocular muscle enlargement.
17例因格雷夫斯病导致中度严重眼病的患者接受了钴或超高压放射治疗。所有患者均主诉有复视。平均眼球突出值为21.4毫米。3例患者（18%）显示出良好反应，7例（41%）为中度反应，7例为轻微或无反应。改善主要见于软组织改变和复视，而仅5例患者眼球突出有所减轻。除1例经计算机断层扫描显示有明显眼外肌受累的患者外，其他所有患者对治疗均有反应。这些数据表明，对于进行性眼病患者，尤其是伴有眼外肌增大的患者，可能需要进行放射治疗。
