Department of Chest Diseases, University of Health Sciences, Izmir Tepecik Training and Research Hospital, Izmir, Turkey.
Department of Chest Diseases, University of Health Sciences, Dr. Suat Seren Training and Research Hospital for Chest Diseases and Thoracic Surgery, Izmir, Turkey.
Arch Iran Med. 2023 Jul 1;26(7):374-380. doi: 10.34172/aim.2023.57.
The risk of recurrence in pulmonary embolism is the highest in the first week after the acute event. Although it decreases over time, it may remain high for months depending on compliance with treatment and the nature of the underlying risk factor. Our study aimed to identify risk factors that lead to recurrence in pulmonary thromboembolism (PTE) patients and establish an easy-to-use scoring system that determines the risk of recurrence after the first embolism.
We retrospectively evaluated 1452 patients who were diagnosed with acute PTE between 7/1/2014 and 7/1/2019. Demographic data, comorbidities and clinical data of the patients, and risk factors were recorded. The relationship of the examined parameters with recurrent PTE was evaluated.
Diabetes mellitus (DM), hypertension, obesity, and the presence of at least one hereditary risk factor were found to be associated with recurrence. The sensitivity of our score was 66.9%, the specificity was 63.2%, the positive predictive value was 19%, and the negative predictive value was 93.7%. The risk of recurrence in the patients identified as high-risk in the scoring system was 3.47 times higher than those identified as low-risk.
In terms of risk of recurrence, special attention should be paid to patients with diabetes, HT, obesity and any of the hereditary risk factors. Using scoring systems to determine the risk of recurrence will be valuable and interesting as it is easy-to-use, gives quick results and provides quantitative results.
肺栓塞(PE)在急性事件后第一周的复发风险最高。尽管随着时间的推移风险会降低,但在几个月内仍可能保持较高水平,具体取决于治疗的依从性和潜在风险因素的性质。我们的研究旨在确定导致肺血栓栓塞症(PTE)患者复发的风险因素,并建立一个易于使用的评分系统,以确定首次栓塞后复发的风险。
我们回顾性评估了 2014 年 7 月 1 日至 2019 年 7 月 1 日期间诊断为急性 PTE 的 1452 例患者。记录了患者的人口统计学数据、合并症和临床数据以及风险因素。评估了检查参数与复发性 PTE 的关系。
发现糖尿病(DM)、高血压、肥胖以及至少存在一种遗传性风险因素与复发相关。我们的评分系统的敏感性为 66.9%,特异性为 63.2%,阳性预测值为 19%,阴性预测值为 93.7%。评分系统中确定为高风险的患者复发风险比确定为低风险的患者高 3.47 倍。
在复发风险方面,应特别关注患有糖尿病、HT、肥胖和任何遗传性风险因素的患者。使用评分系统来确定复发风险将是有价值和有趣的,因为它易于使用,结果快速,并提供定量结果。