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[肺栓塞的临床、实验室及计算机断层扫描肺动脉造影结果:205例患者的回顾性评估]

[Clinical, laboratory and computed tomography pulmonary angiography results in pulmonary embolism: retrospective evaluation of 205 patients].

作者信息

Duru Serap, Ergün Recai, Dilli Alper, Kaplan Tuğba, Kaplan Bekir, Ardıç Sadık

机构信息

Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Göğüs Hastalıkları Kliniği, Ankara-Turkey.

出版信息

Anadolu Kardiyol Derg. 2012 Mar;12(2):142-9. doi: 10.5152/akd.2012.040. Epub 2012 Feb 3.

Abstract

OBJECTIVE

With this study, we aimed at evaluating demographic data, clinical, laboratory findings in pulmonary embolism (PE) and the relationship of these findings with the embolism location region and responses of the patients to the treatment of the embolism in order to contribute to the patient management in decreasing mortality.

METHODS

Clinical findings, accompanying diseases, risk factors, serum D-dimer and creatinine levels, imaging modalities and mortality rates of 205 patients (female: 98, male: 107) diagnosed with PE were examined retrospectively. The relationship between the qualifier variables was evaluated using Chi-square test.

RESULTS

Average age of the patients was 61.55±14.44 years and 86 (42%) patients were above 65 years. Most common complaint was dyspnea (85%), most frequent coexisting disease was congestive heart failure (19%). Deep vein thrombosis (DVT) (30.7%) was the most frequently seen risk factor. Pulmonary embolism was mostly in the right lobe pulmonary artery (32.1%). It was observed that the higher ages of patients the more frequency of proximal located embolism was (p<0.005), especially lobar artery involvement was observed to be high (p=0.032). An early mortality rate was 4.9% and late mortality rate was 11.2%.

CONCLUSION

In the patients with complaint of dyspnea who are at elder ages and have accompanying diseases, PE should be considered. PE is generally localized in the main pulmonary arteries, which emphasizes crucial importance of early diagnosis and treatment in reduction of mortality.

摘要

目的

通过本研究,我们旨在评估肺栓塞(PE)患者的人口统计学数据、临床及实验室检查结果,以及这些结果与栓塞部位的关系,还有患者对栓塞治疗的反应,以便为降低死亡率的患者管理提供帮助。

方法

回顾性检查205例确诊为PE的患者(女性98例,男性107例)的临床症状、伴发疾病、危险因素、血清D - 二聚体和肌酐水平、影像学检查方式及死亡率。使用卡方检验评估定性变量之间的关系。

结果

患者平均年龄为61.55±14.44岁,86例(42%)患者年龄在65岁以上。最常见的症状是呼吸困难(85%),最常见的并存疾病是充血性心力衰竭(19%)。深静脉血栓形成(DVT)(30.7%)是最常见的危险因素。肺栓塞主要发生在右叶肺动脉(32.1%)。观察到患者年龄越大,近端栓塞的发生率越高(p<0.005),尤其是叶动脉受累情况较高(p = 0.032)。早期死亡率为4.9%,晚期死亡率为11.2%。

结论

对于有呼吸困难主诉、年龄较大且伴有其他疾病的患者,应考虑PE。PE通常位于主肺动脉,这强调了早期诊断和治疗对降低死亡率的至关重要性。

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