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髋关节和膝关节置换术后阿片类药物处方:回顾性队列研究。

Opiate prescription after hip and knee arthroplasty: a retrospective cohort study.

机构信息

Joint Reconstruction Unit, Southland Teaching Hospital, Invercargill, New Zealand.

出版信息

N Z Med J. 2024 Feb 2;137(1589):59-66. doi: 10.26635/6965.6327.

DOI:10.26635/6965.6327
PMID:38301201
Abstract

AIMS

Excessive opiate analgesia in relation to orthopaedic surgery is associated with morbidity and mortality. Pre-operative use of opiates is associated with higher post-operative use. There is little information about opiate prescribing practices in relation to elective total joint arthroplasty (TJA) in New Zealand rural centres. The aims of this study were to describe opiate use before, immediately after and 1 year after TJA, and to compare prescribing practices with local guidelines.

METHODS

A retrospective cohort study of elective primary hip and knee arthroplasties was conducted between January 2018 and April 2019. Opiate use was evaluated from clinical records and from electronic prescribing records and described in morphine milligram equivalents (MME) with a particular focus on pre-operative and post-operative periods, and use after 1 year.

RESULTS

In the study period, 199 patients underwent 203 joint arthroplasties. Of these, data from 157 patients were analysed. Patient data were not analysed because of unavailable files (N=20), non-elective procedures (N=11), bilateral arthroplasties (N=4), deaths (N=4) and incomplete information (N=3). Pre-operative opiates were used by 92 (59%) patients, of whom 70 (76%) were not using opiates after 1 year. There were 126 (80%) patients who were discharged with opiate prescriptions and the vast majority, 121 (96%), did not receive discharge prescriptions that conformed to local guidelines.

CONCLUSION

Despite undergoing joint arthroplasty, about one quarter of patients who had been prescribed opiates before the operation were still receiving opiates after 1 year. There was poor compliance with local guidelines.

摘要

目的

与骨科手术相关的阿片类药物镇痛过度与发病率和死亡率有关。术前使用阿片类药物与术后更高的使用量有关。关于新西兰农村中心择期全关节置换术(TJA)的阿片类药物处方实践,信息很少。本研究的目的是描述 TJA 前后和 1 年后阿片类药物的使用情况,并将其与当地指南进行比较。

方法

对 2018 年 1 月至 2019 年 4 月期间进行的择期初次髋关节和膝关节置换术的回顾性队列研究。从临床记录和电子处方记录中评估阿片类药物的使用情况,并以吗啡毫克当量(MME)表示,特别关注术前和术后时期以及 1 年后的使用情况。

结果

在研究期间,199 名患者接受了 203 次关节置换术。其中,对 157 名患者的数据进行了分析。由于文件不可用(N=20)、非择期手术(N=11)、双侧关节置换术(N=4)、死亡(N=4)和信息不完整(N=3),未对患者数据进行分析。92 名(59%)患者术前使用了阿片类药物,其中 70 名(76%)在 1 年后不再使用阿片类药物。有 126 名(80%)患者出院时开具了阿片类药物处方,绝大多数(96%)患者没有开具符合当地指南的出院处方。

结论

尽管接受了关节置换术,但约四分之一术前开阿片类药物的患者在 1 年后仍在接受阿片类药物治疗。当地指南的遵守情况很差。

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