Bhargava Manish, Vats Hitesh, Singh Ajit, Jaiswal Rohit
Department of Oral Pathology, Manav Rachna Dental College, Faridabad, Haryana, India.
Department of General Pathology, OP Chaudhary Hospital, Lucknow, Uttar Pradesh, India.
J Oral Maxillofac Pathol. 2023 Oct-Dec;27(4):780. doi: 10.4103/jomfp.jomfp_379_23. Epub 2023 Dec 20.
Mucoepidermoid carcinoma (MEC) is a rare salivary gland malignancy characterized by diverse cellular components. This case report presents a unique instance of low-grade MEC in a 28-year-old female, emphasizing the importance of accurate diagnosis and tailored management. The patient exhibited a painless, enlarging lower lip swelling over a year, with imaging suggestive of a fibrolipomatous lesion. Surgical excision was successfully performed, with subsequent histopathological analysis displaying mucinous cystic spaces, varied epithelial cell types and other characteristic features consistent with MEC. The case findings aligned with hallmark MEC features are seen in established literature, highlighting the significance of precise diagnosis and grading for appropriate management. This report contributes to the understanding of MEC's varied presentations and underscores the importance of thorough: histopathological examination, lower lip, mucoepidermoid carcinoma clinical evaluation, accurate histopathological analysis and interdisciplinary collaboration. The case highlights the value of considering MEC in younger patients, even with atypical presentations, and encourages ongoing exploration of diagnostic and therapeutic strategies to improve patient outcomes.
黏液表皮样癌(MEC)是一种罕见的唾液腺恶性肿瘤,其特征是具有多种细胞成分。本病例报告展示了一名28岁女性发生的低级别MEC的独特病例,强调了准确诊断和个性化治疗的重要性。患者下唇出现无痛性肿大超过一年,影像学检查提示为纤维脂肪性病变。成功进行了手术切除,随后的组织病理学分析显示有黏液性囊腔、多种上皮细胞类型以及其他与MEC相符的特征性表现。病例结果与已发表文献中MEC的标志性特征一致,凸显了精确诊断和分级对于恰当治疗的重要性。本报告有助于理解MEC的多样表现,并强调了全面的组织病理学检查、下唇黏液表皮样癌的临床评估、准确的组织病理学分析以及多学科协作的重要性。该病例突出了在年轻患者中考虑MEC的价值,即使表现不典型,也鼓励持续探索诊断和治疗策略以改善患者预后。