Department of Neuroscience, University of Copenhagen, Denmark.
Structure. 2024 Feb 1;32(2):120-121. doi: 10.1016/j.str.2024.01.001.
In this issue of Structure, Hall et al. investigate the binding modes of anillin-like Mid1. During cytokinesis, Mid1 connects the contractile ring to the plasma membrane. Using computer simulations, the authors demonstrated how this connection is established via the L3 loop of the C2 domain.
在本期《结构》杂志中,霍尔等人研究了肌球蛋白结合蛋白样 Mid1 的结合模式。在细胞分裂过程中,Mid1 将收缩环连接到质膜上。作者通过计算机模拟,演示了如何通过 C2 结构域的 L3 环建立这种连接。