Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; Department of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, Milan, Italy.
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.
Endocr Pract. 2024 Apr;30(4):380-383. doi: 10.1016/j.eprac.2024.01.012. Epub 2024 Feb 1.
To evaluate the effects of bilateral dorsolateral prefrontal cortex high-definition transcranial direct current stimulation (HD-tDCS) on glycemic excursions during a time-trial performance in elite cyclists with type 1 diabetes (T1D).
In a double-blind, randomized crossover order, 9 elite cyclists with T1D (no complications) underwent either HD-tDCS (F3 and F4) or control (SHAM) and completed a constant-load trial at 75% of the second ventilatory threshold plus a 15-km cycling time trial.
Real-time continuous glucose monitoring revealed similar glycemic variability between the 2 conditions, showing a significant effect of time but no interaction (stimulation × time) or stimulation effect.
Because glycemic control is crucial for both health and performance, these findings suggest that HD-tDCS could be safely used to enhance performance in athletes with T1D and potentially in a broader active T1D population.
评估双侧背外侧前额叶皮质高频经颅直流电刺激（HD-tDCS）对 1 型糖尿病（T1D）精英自行车运动员计时赛表现期间血糖波动的影响。
在一项双盲、随机交叉试验中，9 名无并发症的 T1D 精英自行车运动员分别接受了 HD-tDCS（F3 和 F4）或对照（假刺激）治疗，并完成了 75%第二通气阈加 15 公里自行车计时赛的等负荷试验。
实时连续血糖监测显示两种情况下的血糖变异性相似，表现出时间的显著影响，但无刺激×时间的相互作用或刺激效应。
由于血糖控制对健康和表现都至关重要，这些发现表明，HD-tDCS 可安全用于增强 T1D 运动员的表现，并且可能适用于更广泛的活跃 T1D 人群。
